Senior Manager ​/ Associate Director, Gross-to-Net & Revenue Planning

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.

With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

Position Summary: The Senior Manager / Associate Director, Gross-to-Net (GTN) & Revenue Planning will own gross-to-net, revenue forecasting, and commercial operating expense forecasting for Orca Bio's first commercial product. Reporting to the Senior Director/Head, FP&A, this role establishes the accrual methodology, forecast architecture, documentation, and monthly cadence that a newly commercial company requires — in a product setting where individual transactions are material and where there is limited precedent to inherit.

The position requires strong technical judgment, cross-functional partnership, and deep expertise in pharmaceutical revenue deductions and government pricing.

This is a hands-on individual contributor role. The successful candidate will build the models, run the monthly process, reconcile the underlying data, and present results directly to executive leadership and external auditors.

• Own the monthly and quarterly gross-to-net accrual and reserve process end to end, including distribution and title fees, specialty pharmacy fees and prompt-pay discounts, Medicaid rebates, 340B, FSS/VA pricing, chargebacks, and other revenue deductions as the channel develops
• Establish and maintain accrual rate methodology and assumption documentation for a newly launched product with limited claims history
• Execute rate true-ups as actual claims and utilization data mature, and explain the resulting variances
• Build and maintain reserve roll-forwards, reserve-to-payment reconciliations, and rate variance analyses
• Serve as the finance owner of third-party government pricing calculations — AMP, Best Price, non-FAMP, Medicaid unit rebate amount, and 340B ceiling price — validating vendor output in partnership with Market Access and supporting executive certification
• Monitor payer mix, channel dynamics, and reimbursement developments, and translate them into forecast and reserve implications

• Partner with Commercial Operations & Strategy on the revenue forecast build, from treatment-center-level demand through gross sales to net revenue
• Support the modeling of drivers specific to cell therapy, including authorized treatment center activation and ramp, referral-to-infusion conversion, manufacturing capacity and slot constraints, donor eligibility yield, and vein-to-vein timing
• Work with Commercial Operations & Strategy to deliver the monthly latest estimate, quarterly reforecast, annual budget, and long-range plan inputs for revenue and gross-to-net
• Produce variance analysis and written commentary for executives and Board reporting
• Partner with Commercial and Market Access to align demand assumptions with field intelligence and account activation plans

• Partner with Commercial, Market Access, Patient Services, and Medical Affairs on budget, latest estimate, and long-range planning for commercial operating expenses
• Own budget-versus-actual reporting, accrual review, and variance commentary for commercial functions
• Track headcount and program spend against plan, and support functional leaders in managing their budgets

• Partner with Accounting on the revenue close, including journal entries, account reconciliations, flux analysis, and cut-off
• Ensure compliance with GAAP, ASC 606, SOX (as applicable), and internal controls
• Build and maintain audit-ready documentation and control narratives for gross-to-net and revenue processes
• Serve as a primary point of contact for external auditors on gross-to-net methodology and revenue forecasting assumptions
• Contribute analysis and peer benchmarking to technical accounting positions on revenue deductions and other ASC 606 matters

• Own the flow of finance data from third-party logistics, specialty pharmacy, and distribution partners into forecast and accrual models
• Support implementation and maintenance of ERP and planning systems as they relate to revenue and gross-to-net
• Drive automation and reporting improvements as transaction volume grows
• Support gross-to-net and revenue process design for ex-US markets as they are added

• Bachelor's degree in Finance, Accounting, Economics, or related field
• 7+ years of…