Sr. Research Associate - Urology

Position: Sr. Research Associate 3 - Urology
##
** Current Employees:
** If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click  to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this .The University of Miami UHealth Department of Urology has an exciting opportunity for a full time Sr.

Research Associate 3, SOM to work at the UHealth Medical Campus.

The Sr. Research Associate 3, SOM will perform research elucidating fundamental mechanisms of human biology with some relevance to prostate, kidney, or bladder cancer. The overarching goal of the institute’s research program is to define the underlying biochemical and clinical behavior of prostate, kidney, and bladder cancers in order to identify new strategies to prevent symptoms and death. Areas of interest include fundamental mechanisms biochemistry, metabolism and genetics.

The Sr. Research Associate 3, SOM supports the University’s research goals and objectives by engaging in complex experiments and investigations under the supervision of managing staff.
** Please submit a cover letter with your online application.
**** CORE JOB FUNCTIONS
*** Contributes to basic and applied research activities by collecting and analyzing data.
* Understands and interprets research protocols and procedures.
* Maintains an overview of relevant research findings.
* Ensures all research is undertaken according to good research practice.
* Designs, evaluates, and implements methods and protocols for assigned research projects.
* Recommends purchase of new equipment for research projects.
* Writes scientific articles and manuscripts for publication and presentation.
* Oversees and ensures the safe handling of radioactive and hazardous materials.
* Prepares analytical reports relative to research data.
* Adheres to University and unit-level policies and procedures and safeguards University assets.
*** This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.
***** CORE QUALIFICATIONS
***
* Education:

*** M.S. in biochemistry, chemistry, molecular biology or another relevant field required
* Minimum 3 years of relevant experience
*
* Experience:

** Minimum 3 years of relevant experience required
** Knowledge, Skills and Attitudes:
*** Has the appropriate expertise in discovery of molecular, biochemical or chemical mechanisms; and is highly driven.
* Outstanding verbal and communication skills are required.
* Skill in collecting, organizing, and analyzing data.
* Ability to recognize, analyze, and solve a variety of problems.
* Ability to exercise sound judgment in making critical decisions.
** DEPARTMENT ADDENDUM
**** Department Specific Functions
** Our laboratory focuses on mechanistic discovery to understand the metabolic and molecular mechanisms of androgen synthesis and androgen receptor gain-of-function that lead to resistance to hormonal therapy.  Our work is revealing fundamental endocrine mechanisms in both normal physiology and disease, including stress, aging, and glucocorticoid resistance, that will lead to broad applications to oncology and cancer physiology.
** Specific areas include:
*** Metabolic and genetic changes required for hormone therapy resistance in prostate and breast cancers
* Discovery of entirely new mechanisms of endocrine physiology and regulation
* Clinical validation in patients and clinical trials using innovative approaches
* Animal models of advanced cancer for translational and therapeutic studies
* Identifying targets for the development of new pharmacologic therapies
* Drug discovery for new therapies

This position is ideal for an individual with a strong interest in rapid translation of basic mechanistic discoveries to the bedside as this is a principal goal of the Sharifi Laboratory. For example, we have shown that our discovery of a gain-of-function in a steroid-synthesizing enzyme is a predictive biomarker of poor outcomes after hormonal therapy (Hearn, et al.
*** Lancet Oncol*.
** 2016;17:1435-44;
*** JAMA Oncol*.
** 2018;4:558-62;
*** JAMA Oncol*.
**…