Sr. Manager – AI and R&D Infrastructure

Sr. Manager, AI and R&D Infrastructure

Histo Sonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, Histo Sonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women's health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.

Location:

Plymouth, MN

Position Summary (Why this role matters):

The Sr. Manager, AI and R&D Infrastructure leads the team responsible for cloud platforms, AI automation, and systems imaging capabilities across the CTO organization. This role ensures the reliability, security, compliance, and continuous evolution of critical infrastructure and tools that support software development, research, clinical operations, and product innovation. The position partners closely with technical and business leaders to execute strategy, develop talent, drive operational excellence, and foster a culture of engineering excellence, accountability, and continuous improvement.

Key Responsibilities (What you'll do):

• Provide leadership to a team of cloud platform engineers, agentic AI developers, and systems imaging specialists; establish a high-performance team culture grounded in engineering excellence, security by design, continuous learning, and clear accountability for outcomes
• Attract, hire, develop, and retain top technical talent; actively shape the team's organizational structure, role definitions, and career pathways to build durable capability aligned with Histo Sonics' long-term technical strategy
• Contribute to and execute the AI and R&D Infrastructure team's strategy and multi-quarter roadmap in partnership with the Sr. Director; translate the CTO organization's technical and business objectives into a coherent set of product cloud platform, AI automation, and infrastructure investments that deliver measurable value
• Operate with autonomy in setting day-to-day priorities; make informed recommendations about where the team's time and resources are best invested, balancing immediate operational needs against strategic capability-building; communicate the rationale for these decisions clearly to stakeholders at all levels
• Represent the AI and R&D Infrastructure team in Product Development organization planning, architecture forums, and cross-functional leadership discussions; advocate effectively for the team's priorities, surface emerging risks and opportunities, and influence decisions that affect the broader CTO organization
• Establish the team as a trusted, proactive partner across the organization by building and maintaining strong partnerships with the Sr. Director – Software Platforms and Technology Strategy, software engineering leadership, Information Systems, Security, Data Privacy, Quality, and Regulatory stakeholders.
• In partnership with Information Systems and Security, establish and evolve product cloud infrastructure governance: policy-driven controls, reusable IaC templates and modules with best practices embedded, enforceable guardrails, and organizational standards for cost tracking, naming, tagging, alerting, logging, and observability; hold the team accountable for consistent application of these standards
• Partner with Information Systems leaders for cloud resource hierarchy, subscription management, and management group governance at the highest organizational level; ensure compliance and security requirements for cloud infrastructure are tracked, communicated, and addressed
• Guide the team in evaluating and adopting new cloud tools, architecture patterns, and platform capabilities; champion a culture of continuous improvement and deliberate technical evolution
• Guide the team in maintaining Infrastructure as Code practices, reusable module…