Research Professional - Research Lab

About the Job

This is a position in Dr. Andrew Adams' Lab within the Department of Surgery at the University of Minnesota. We are looking for a motivated researcher with a strong interest in basic and translational clinical research. A background in immunology or a related field (molecular biology, virology, genetics, etc) is a bonus! This position works under the direction of our higher-level researchers in the lab and under supervision of Dr.

Andrew Adams and Dr. Neal Iwakoshi. The purpose of the Researcher 1/2 position is to assist in these areas of investigation of our lab: (1) costimulation blockade and costimulation independent rejection (2) xenotransplantation (3) transplant diagnostics (4) transplant outcomes.

This is a great opportunity for a BA/BS level scientist to join a cutting-edge academic laboratory focused on developing novel cellular and molecular therapies to prevent graft rejection and induce immune transplant tolerance.

• Perform a variety of basic molecular and biochemical analyses on animal specimens, including fluorescence microscopy analyses, flow cytometry, cell isolation, freeze/thaw of archived cells, cell culture; flow cytometric characterization and purification (sorting); biochemical assays on DNA, RNA/protein. Preparation of media and various molecular biology techniques.
• Collect and integrate data from multiple sources. Review literature for relevant sources of scientific information and methods.
• Mouse colony management, such as breeding, checking for new litters, weaning infant mice.
• Maintain laboratory equipment, order and stock items.
• Keep detailed records of all experiments and procedures in laboratory notebooks, databases, spreadsheets, and web-based applications.
• Conduct background literature research on relevant topics including current methods, reagents, and ethics.
• Prepare media, enzymes, and solutions under sterile conditions in large quantities.

• Perform intermediate/advanced molecular and biochemical analyses on animal and human specimens, including fluorescence microscopy analyses, flow cytometry, cell isolation, freeze/thaw of archived cells, cell culture; flow cytometric characterization and purification (sorting); biochemical assays on DNA, RNA/protein. Preparation of media and various molecular biology techniques. These analyses are to be followed up with statistical analysis and preliminary interpretation of results to identify trends or anomalies.
• Help monitor and train undergraduate student workers and volunteers.
• Oversee the use of laboratory equipment, training personnel/volunteers and maintaining performance and maintenance records.
• Draft sections of primary research manuscripts, prepare publication-quality figures, and provide data summaries for grant applications.
• Researcher 2s will generally be expected to perform tasks with less direction, more independence and function as a resource for more junior researchers, volunteers and students.

Required Qualifications for 8351RL (Researcher
1):

• BA/BS or equivalent combination of education and experience to total at least four years.

Required Qualifications for 8352RL (Researcher
2):

• BA/BS and at least 2 years of related experience or equivalent combination of education and work experience to total at least six years.

Required Qualifications for 8351RL & 8352RL (Researcher 1 &
2):

• Excellent verbal and written communication skills.
• Demonstrated ability to learn complex processes or procedures and desire to learn and grow in a scientific field.
• Team player who has demonstrated experience successfully working with others to achieve a common goal.
• Ability to work on-site, M-F and flex schedule as needed based on the activities of the laboratory.
• Will be required to stand for several hours at a time and required to lift and move up to 25lbs.

Preferred Qualifications:

• Experience performing sterile cell culture. Ability to independently troubleshoot and resolve technical problems.
• Understanding of laboratory protocols and necessary steps to ensure compliance with protocols and animal use regulatory standards. Biological tissue handling & processing, routine lab‑related tasks.
• Previous experience following written protocols and maintaining accurate and complete documentation of all procedures and experiments including demonstrated ability to readily perform all necessary laboratory equations and calculations.
• Experience reporting effectively on the progress and direction of individual projects.
• Previous experience using software to track data and output data into visual representation.

To learn more about the Department of Surgery, please visit (Use the "Apply for this Job" box below)..

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