Associate Scientist, Cell Signaling and Assay Development

Associate Scientist, Cell Signaling and Assay Development

Minneapolis, MN

POSITION SUMMARY:

Reporting to the Director, Tissue or Assay / Laboratory Manager, the Associate Scientist will play a key role in the development, validation, and execution of live‑cell assays supporting translational oncology research. This individual will contribute to advancing precision medicine by characterizing cell signaling pathways and ensuring the generation of high‑quality, reproducible data in a high‑complexity, CLIA‑certified laboratory environment.

PRIMARY

RESPONSIBILITIES AND DUTIES:

Assay Development & Validation:

Design, develop, validate, and transfer cell signaling and pathway‑based assays across multiple cancer tissue types.

Cell Culture & Maintenance:

Culture, maintain, and ensure consistency of human cell lines and primary samples under varied laboratory conditions. Perform phenotypic and pathway characterization using cell‑based assays and integrate informatics data to identify and classify cell types.

Regulatory Compliance:

Adhere to CAP/CLIA standards and HIPAA regulations, maintaining compliance within a high‑complexity clinical testing environment.

Cross‑Functional

Collaboration:

Partner with Scientific Directors and laboratory leadership to troubleshoot assays, optimize protocols, and improve laboratory efficiency.

Quality & Data Integrity:

Monitor and maintain quality control processes, including QC metrics, preventive maintenance (PM), and standard operating procedures (SOPs), ensuring data accuracy and reliability.

QUALIFICATIONS AND SKILLS:

Education & Experience:

• Ph.D. in a relevant scientific discipline with experience in activity‑based live‑cell assay development for small molecules; OR
• Master’s degree with 5+ years of relevant industry experience; OR
• Bachelor’s degree in a scientific field with 6–8+ years of relevant industry experience.

Required Technical

Skills:

• Hands‑on experience with human cell culture techniques
• Experience with microplate‑based live‑cell assays
• Knowledge of multiparametric (e.g., 5‑channel) cell cytometry
• Experience with immunochemistry techniques
• Strong understanding of laboratory quality systems, including QC, PM, and SOP adherence

Preferred Qualifications:

• Experience with Jess (Protein Simple) systems
• Experience working with human primary cells

Celcuity is an Equal‑Opportunity Employer.

Celcuity is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are competitive. For this role, the anticipated base pay range is $90,000–$125,000 DOE. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.