Executive Director, Early Clinical Development

Role

Executive Director of Early Clinical Development, leading the strategic planning and operational execution of clinical programs for Revolution Medicines' RAS(ON) inhibitors in oncology.

• Oversee clinical trial design, site management, data interpretation, regulatory interactions, and cross-functional team leadership
• Develop and implement development strategies aligned with scientific and regulatory goals
• Manage stakeholder relationships and ensure milestone achievement from early trials to potential regulatory submissions

• MD, PhD, or equivalent with 13+ years in pharma/biotech or academia
• Extensive experience in clinical trial design, early-phase drug development (Phase
  1), regulatory interactions, and multi-disciplinary leadership
• Strong knowledge of GCP, ICH, FDA, EMA guidelines
• Proven track record of successful clinical development and regulatory submissions
• Excellent strategic, communication, and leadership skills

• Experience with NDA/BLA submissions, regulatory authority interactions, phase IV studies, and process improvements
• Demonstrated ability to serve as a company spokesperson and lead enterprise-level initiatives

oncology, RAS pathway, novel targeted therapies, clinical-stage molecules, early to late-phase development, regulatory engagement, cross-functional collaboration, onsite Redwood City, CA; no explicit travel expectations stated.