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Senior Medical Science Liaison - External Research

Job in California, Moniteau County, Missouri, 65018, USA
Listing for: Tempus AI, Inc.
Full Time position
Listed on 2026-07-24
Job specializations:
  • Research/Development
    Clinical Research
Salary/Wage Range or Industry Benchmark: 120000 - 190000 USD Yearly USD 120000.00 190000.00 YEAR
Job Description & How to Apply Below
Position: (Senior) Medical Science Liaison - External Research
Location: California

We are looking for a high‑performing and experienced Senior Medical Science Liaison (Sr.MSL) to support the commercial, research, and educational objectives of Tempus. The role is field‑based, primarily in Chicago or a US location, with a strong clinical and scientific background in oncology, genomic testing, and excellent communication skills to educate healthcare providers about Tempus assays and technologies.

Responsibilities
  • Provide medical support to Clinical MSLs and other cross‑functional colleagues to ensure successful management of research discussions and intake of study concepts for potential collaborations.
  • Engage academic KOLs and investigators in oncology to work on collaborative external research—including investigator‑initiated trials, assay grants for biobank samples or prospective trials, and real‑world retrospective data studies.
  • Proactively seek opportunities for incorporating Tempus assays into high‑impact external research, including collaborations with cooperative group trials and pharmaceutical trials (company‑sponsored or investigator‑led).
  • Identify data gaps and clinical unmet needs in key cancer types for each Tempus assay platform or molecular signature.
  • Assess study proposals received from investigators for completeness, clarity, feasibility, clinical and scientific merit, and strategic value.
  • Serve as a research liaison between internal data scientists and external academic investigators for all study‑related communications, including iterative workflows in reviewing analyses and study results.
  • Support medical writing of abstracts, data presentations, and manuscripts on external research study collaborations.
  • Support engagements with potential research collaborators through regularly scheduled specialty‑specific Tempus+ Working Group meetings, which include faculty from a broad range of academic and community oncology centers.
  • Manage and leverage KOL relationships gained through study collaborations to support broader research and educational interests for the organization.
  • Collaborate with the Medical Affairs Team and other internal teams in supporting medical advisory boards.
  • Contribute to team tracking and management of the External Research Portfolio, including abstract and publication planning/execution efforts.
  • Support the development and management of a Medical Research Strategy and Scientific Exchange Plans to guide the prioritization of new external research investments through biannual clinical reviews of unmet needs for biomarkers for immunotherapy and targeted therapies, tumor response monitoring, and minimal residual disease in each cancer type.
  • Liaison cross‑functionally with internal stakeholders in Medical Affairs, Marketing, Sales, R&D, Clinical Development, Biostatistics, Bioinformatics, and AI engineers.
  • Attend oncology conferences and cooperative group research meetings to connect with KOLs and provide comprehensive meeting synopses and summaries of high‑impact scientific content.
  • Continuously update internal stakeholders on relevant medical and scientific knowledge and proactively share market intelligence.
Required Skills
  • 2+ years of Medical Science Liaison or other Medical Affairs experience in diagnostics, biotech, or pharmaceutical industries.
  • Ability to project manage up to 25–30 individual study collaborations in different phases of execution.
  • Ability to work with commercial field‑based sales and business account managers.
  • Strong communication, liaison, and expectation‑management skills with KOLs and academic researchers.
  • Existing KOL relationships in oncology are preferred.
  • Strong public‑speaking skills and ability to communicate complex scientific concepts internally and externally.
  • Working knowledge of statistical methods and clinical trial design principles.
  • Familiarity with genomic laboratory‑developed testing (LDT), CLIA‑88, CAP, and the Sunshine Act (2013).
  • Self‑starter with an ownership mindset, able to deliver on tight timelines.
  • Ability to travel up to 50%.
Educational and Experience Requirements
  • Advanced scientific or medical degree (PhD, PharmD, MD, MSN, BSN).
  • Advanced knowledge and experience in molecular oncology, biomarkers, and diagnostic…
Position Requirements
10+ Years work experience
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