Research Assistant or Associate in Cell Therapy; Calibr

Research Assistant or Associate in Cell Therapy (Cali )

Below you will find the details for the position including any supplementary documentation and questions you should review before applying for the opening.

05911

Cali

Full Time

Research Assistant or Associate in Cell Therapy (Cali )

Job . This position is with the California Institute for Biomedical Research (Cali ).

The California Institute for Biomedical Research (Cali ) is a not-for-profit research institute located in La Jolla, California. Cali  is focused on innovative early-stage translational research in the areas of regenerative medicine, cancer biology, cardiovascular and metabolic disease, immunology and infectious disease.

This position will work within a small team of interdisciplinary scientists to translate novel cellular therapies for the treatment of cancer into human clinical trials. Specifically, this position works alongside other research scientists in the development of Cali ’s novel universal, switchable CAR
-T cell platform. The Research Assistants or Research Associate will play an integral role in Cali ’s target discovery program which will focus on the translation of novel CAR
-T strategies to solid tumors.

• Cell biology including working with primary human immune cells and culturing multiple cell lines including, but not limited to, common tumor cell lines used in immuno-oncology research.
• Design and execution of project plans involving immune cell profiling, cell processing from xenograft models, cytotoxicity, proliferation, activation, cell viability, and survival assays with a strong focus on flow cytometry.
• Generation of reagents for projects including preparation of lentivirus for transduction of both established cell lines and primary immune cells.
• Molecular biology experiments including DNA and protein preparation from cells, immunoprecipitation, Western blots, etc. will be within the scope of work.
• Preparation of reports and presentation of results at regular team meetings.

“The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.”

California

This position is with the California Institute for Biomedical Research (Cali ).

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions.

Details of established essential functions for this position will be addressed/discussed during the interview process

• A strong background in cell culture is essential.
• Hands on experience in cellular immunotherapies are strongly preferred.
• Experience and knowledge of the immune system are a required. Experience in T cell biology, tumor immunology, as well as other immune components is preferred.
• Hands-on experience with in vitro assays commonly used in immuno-oncology, and experience preparing reagents for in vivo assays.
• In vivo experience preferred but not required.
• Experience with multi-color flow cytometry and flow data analysis is required.
• Experience with cell transfection and transduction systems is preferred.
• Experience with molecular biology techniques is preferred.
• Experience using Prism, Flow…