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Vice President, Portfolio Chemistry

Job in California, Moniteau County, Missouri, 65018, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-10-06
Job specializations:
  • Research/Development
    Drug Discovery
Salary/Wage Range or Industry Benchmark: 294000 - 367000 USD Yearly USD 294000.00 367000.00 YEAR
Job Description & How to Apply Below
Role

Vice President, Portfolio Chemistry, leading Revolution Medicines' medicinal chemistry and related sciences to advance oncology programs from hit validation through development candidate nomination.

Responsibilities

develop and execute long-term chemistry strategy, integrate computational, AI/ML, and digital tools into discovery workflows, oversee organizational planning, resource allocation, and foster collaboration across research functions to ensure seamless program progression.

Requirements
  • Ph.D. in Organic Chemistry;
  • 16+ years in industrial drug discovery with proven leadership supporting multiple discovery programs;
  • deep expertise in medicinal chemistry, structure-based design, and optimization;
  • experience with computational chemistry and external collaborations.
Preferred
  • oncology drug discovery experience,
  • successful IND filings,
  • clinical candidate delivery,
  • patents/publications,
  • experience with modalities like molecular glues or ADCs.
High-value specifics

leadership in oncology small-molecule programs, from hit validation to IND-enabling studies, with experience integrating AI/ML into discovery.

Collaboration

Collaboration with senior research leadership, external CROs, and cross-functional teams is essential.

Work setup

onsite at Redwood City, CA, with salary range $294K-$367K, inclusive of competitive compensation, equity, and benefits.

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