Senior Research Engineer, Research & Early Development

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

Join Roche, where every voice matters.

The Position Roche is working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing, resulting in a sample in, result out workflow.

Our Systems Technology Group, part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking an enthusiastic, team-oriented Senior Research Engineer to join the effort.

In this role, you will tackle a variety of tasks and projects that will help us advance our technology and hardware related to our next-generation DNA sequencing systems. Your efforts will cover many aspects related to the fabrication, assembly and testing of custom devices, fixtures, breadboards and prototypes.

• Designing and fabricating parts and devices using CNC machining, laser cutting, 3D printing and other shop and prototyping tools
• Assembling, testing, characterizing, and troubleshooting complex fluidic and electromechanical systems and devices
• Optimizing workflows, protocols, and assays, while collecting, analyzing, and interpreting data to drive technical progress
• Operating, repairing and maintaining various lab equipment and instruments, including custom systems such as breadboards and fixtures
• Utilizing various types of metrology instruments to characterize parts and evaluate manufacturing methods
• Collaborating with other scientists and engineers

• You have a Ph.D. in Bioengineering or a closely related discipline
• You have 2-5 years of relevant research and early development experience in the life science industry

• You have a demonstrated success in designing, modeling, building, operating, and troubleshooting hardware, fixtures, and breadboards integrated with fluidic, pneumatic, thermal, and optical subsystems
• You have a demonstrated level of proficiency in 3D CAD software (e.g., Solid Works) for detailed design and the creation of manufacturing drawings
• You have strong creative problem-solving skills, with the ability to troubleshoot complex hardware, software, and chemistry interfaces
• You have demonstrated hands-on experience with DNA sequencing or other molecular biology-based workflows (nucleic acid extraction methodologies and purification techniques, library preparation, and target enrichment)
• You have a demonstrated level of proficiency in operating and interpreting data from bioanalytical instruments, including qPCR, dPCR, Bioanalyzer/Tape Station, Qubit Fluorometer, and Nano Drop UV-Vis Spectrophotometer
• You have demonstrated a strong grasp of engineering and chemistry fundamentals

• You have a solid publication record, including at least one first-authored publication
• You have a level of technical skills paired with strong organizational, communication, and writing capabilities
• You have strong interpersonal and communication skills, with the ability to explain…