Sr. Manager, Bioinformatics

Roche is seeking a visionary and deeply technical leader to champion the customer‑facing bioinformatics and software strategy for our revolutionary Axelios sequencing platform.

• Customer Advocacy & Technical Enablement:
  Serve as the primary executive‑level technical contact for new customers, driving deep adoption of the XOOS bioinformatics ecosystem across major clinical and research applications.
• Team Leadership:
  Build, inspire, and manage a high‑performing team of customer‑facing bioinformatics scientists and solutions architects.
• Bespoke Solution Engineering:
  Lead the creation of customized workflows, data analysis pipelines, and software integrations to solve unique customer pain points and accelerate Axelios platform adoption.
• Collaborative Research:
  Partner with strategic early‑adopter customers on collaborative research projects, co‑authoring whitepapers, and demonstrating the unique capabilities of Axelios non‑SBS data.
• Cross‑Functional Feedback Loop:
  Act as a critical strategic partner to internal Bioinformatics and Software R&D teams, synthesizing market requirements, feature requests, and technical friction points into the product roadmap.
• Commercial & Technical Strategy:
  Collaborate with Sales and Product Management to support high‑value customer engagements, technical evaluations, and complex contract closures.

This position is based on‑site in Santa Clara, CA or San Diego, CA (hybrid). Relocation benefits are not being offered for this role.

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field with 4+ years of industry experience; or a Master’s degree with 6+ years of industry experience.
• 8+ years progressive experience in next‑generation sequencing (NGS) bioinformatics, with a demonstrated track record of leadership in an industry setting.
• Significant expertise and comprehensive knowledge of the NGS landscape, clinical genomics space, and secondary/tertiary data analysis pipelines.
• Demonstrated leadership experience.
• High proficiency with cloud architectures (AWS, Azure, or GCP), modern software development practices, pipeline frameworks (Nextflow, Snakemake), and scripting languages (Python, R).
• Experience in product commercialization, go‑to‑market execution, or technical customer enablement.
• Preferred:
  Experience working with non‑SBS technologies (e.g., long‑read sequencing or alternative modalities).
• Exceptional communication, presentation, and relationship‑building skills.
• Ability to navigate complex, sensitive technical discussions with world‑class clinical and scientific executives.
• Ability to navigate the complexities of a global organization, adapt to changing business needs, and work collaboratively within a diverse and inclusive environment.
• Excellent organizational skills, including the ability to efficiently evaluate, prioritize, and handle multiple changing projects and priorities; complete work in a timely, accurate, and thorough manner.

Expected salary range: $170,500 - $316,600, plus discretionary annual bonus and benefits.

Competitive benefits package, including health, vision, and dental coverage, retirement plan, and other employee benefits available to eligible employees.

Roche is an equal opportunity employer. If you have a disability and need an accommodation in the online application process, please complete the accommodations form.