Assistant Research Professor - Precision Oncology of Gastrointestinal Cancers

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we are making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our faculty and staff are driven by a common mission: to contribute innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting‑edge research.

Led by Dr. Ajay Goel, Professor and Founding Chair of the Department of Molecular Diagnostics and Experimental Therapeutics, our multidisciplinary research group includes basic researchers, gastroenterologists, surgeons, oncologists, and bioinformaticians. The position has the potential to become tenure‑track upon receiving grant funding lasting 3–5 years from a federal agency.

• Development of cell‑free DNA (mutation and methylation), RNA, and exosomal‑based liquid assays for early cancer detection, prognosis, and predictive responses to chemo therapies and targeted drugs.
• Studying the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non‑coding RNAs).
• Understanding the biological implications of the gut microbiome and its translational application in gastrointestinal cancers.
• The genetic basis of early‑onset colorectal cancer (EO‑CRC) and familial/hereditary colorectal cancer.
• The role of extracellular vesicles/exosomes in cancer pathogenesis and as disease biomarkers.
• The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies.
• Cancer prevention and adjunctive role of natural and integrative therapy approaches.

• PhD, MD, or MD/PhD with a strong background and profound knowledge in oncology, cancer biology, immunology, or immunotherapy.
• Prior molecular, cancer biology, and/or translational research experience with evidence of project development and supervision of post‑doctoral fellows and technical staff.
• Evidence of scientific rigor and excellence as documented by high‑impact peer‑reviewed publications, as a first or lead author.
• Evidence of obtaining successful funding from foundations or other extramural resources.
• Documented evidence of mentoring post‑docs, research associates, and others in a research laboratory environment.

City of Hope is an equal opportunity employer.