Staff Scientist - Hematologic Malignancies and Cancer Immunotherapy

Join the forefront of groundbreaking research at City of Hope
, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission:
Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Marcucci and Zhang Laboratories at City of Hope are seeking a highly motivated Staff Scientist to join our research program in hematologic malignancies and cancer immunotherapy. Our research focuses on leukemia stem cells, the tumor microenvironment, CAR T-cell therapy, bispecific T-cell engagers, and microRNA biology, with the goal of developing novel therapies for leukemia and myeloproliferative neoplasms.

The successful candidate will lead independent and collaborative projects and contribute to high-impact publications and translational research.

• Perform cell culture, lentiviral transduction, and molecular biology experiments.
• Conduct multi-color flow cytometry and data analysis.
• Perform in vivo studies using mouse models, including oral gavage, intravenous, and intraperitoneal injections.
• Analyze data, prepare manuscripts and grant applications, and present research findings.

• Ph.D. in Immunology, Cancer Biology, Hematology, Molecular Biology, or a related field.
• Hands-on experience with cell culture, lentiviral transduction, flow cytometry, molecular biology (e.g., CRISPR/Cas9, qPCR, Western blotting), and mouse studies.
• Excellent communication, organizational, and scientific writing skills.

• Experience with CAR T-cell engineering, patient-derived xenograft (PDX) models, or cancer immunotherapy.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.