Operational Excellence Performance Lead

Overview

Location:

Cambridge, MA

The Operational Excellence Performance Lead is a key member of the EM&S Operational Excellence team, responsible for fostering the SMS (Sanofi Manufacturing System) mindset within External Manufacturing and Supply operations. This role works transversally with Global Business Units (GBUs) to standardize, simplify, and optimize external manufacturing operations with Contract Manufacturing Organizations (CMOs), leveraging lean and SMS 2.0 principles and tools. The position ensures sustainability of the performance roadmap through a comprehensive upskilling program.

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

• Performance Roadmap Deployment: Coordinate, prepare, animate performance workshops focused on cycle time reduction, yield improvement, complex problem solving, and launch readiness. Lead and coordinate execution of related action plan
• Performance Partnership: Act as performance partner for one or more EM&S business units by attending leadership team meetings and performance rituals, supporting early detection of performance gaps and improvement opportunities, and driving prioritization and execution of initiatives
• Performance Management System: Deploy and maintain the EM&S performance management system according to SMS 2.0 standards, including +QDCI, Team Board, and GPS3 board
• Operational Excellence Upskilling Program: Contribute to SMS upskilling program including training, certification, and coaching activities
• Cultural Change Leadership: Champion cultural change in continuous improvement, change management, and problem-solving methodologies

• Bachelors' degree required.
• 7+ years of relevant professional experience.
• Deep knowledge of performance management systems, continuous improvement methodologies, and problem-solving techniques. Proven track record of realizations.
• Expertise in sterile manufacturing and aseptic filling operations
• Expertise in biotech Drug Substance (DS) manufacturing
• Performance-oriented mindset with ability to understand and identify key performance drivers
• Cross-functional agility with demonstrated ability to operate effectively in matrix environments
• Strong communication skills with ability to establish and deliver impactful communications to senior leadership
• Coaching and training capabilities with experience developing others through structured support and feedback
• Change management and stakeholder engagement capabilities
• Fluent in English (written and verbal)
• Experience working with external partners and Contract Manufacturing Organizations (CMOs) is a plus
• SMS certification Intermediate or above (or equivalent Lean/Six Sigma)
• Experience in training, coaching, and people development is a plus

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
• Shape the future of medicine and vaccine delivery with cutting-edge technology, ensuring seamless launches and a resilient global supply.
• Power industry-leading performance by leveraging digital, data, and AI-driven innovation – at…