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Senior Clinical Lead, Early Clinical & Experimental Therapeutics
Job in
Morristown, Morris County, New Jersey, 07960, USA
Listed on 2026-07-04
Listing for:
Scorpion Therapeutics
Full Time
position Listed on 2026-07-04
Job specializations:
-
Research/Development
Clinical Research
Job Description & How to Apply Below
Main Responsibilities
- Design safe, rapid, informative First-In-Human (FIH) oncology studies (incl. natural history, experimental model validation, mechanistic/signal-seeking, Proof-of-Mechanism/Proof-of-Concept) to support early Go/No-Go and pharmacokinetic decisions.
- Plan clinical development steps and integrate into overall development strategy; provide medical/clinical guidance for preclinical data generation/interpretation.
- Make front-line decisions on protocol design/execution, dose escalation, safety, and regulatory-facing information.
- Supervise clinical study execution; oversee and perform medical monitoring.
- Review/interpret results and author ECET-related documentation (consent forms, protocols, study reports; plus clinical pharmacology/ECET components of relevant documents).
- Coordinate oversight of CROs/outsourced activities; ensure cross‑functional communication; lead dose escalation meeting; review adverse event reports; oversee safety monitoring.
- Participate in data review/validation; prepare Key Results Memo and Clinical Study Report.
- Design and conduct FIH to phase 2a studies within timelines; review/approve study documents; coordinate setup/follow-up; ensure Ethics Committee/Health Authority documentation.
- M.D. or M.D./Ph.D.
- 3+ years clinical research experience (Phase 1/2a patient oversight and interpreting preclinical/biomarker data).
- Experience designing/executing early development/exploratory studies; leading cross‑functional teams; medical safety oversight.
- Experience in translational/biomarker research and using emerging digital/AI tools.
- Biomedical knowledge; GCP knowledge; strong verbal/written communication; risk‑management mindset; matrix working; international/intercultural collaboration.
- MD+PhD (or equivalent bench experience);
- Global pharma experience;
- Combination therapy/cytoplasmic signaling targets;
- Late‑phase trial experience.
- Health and wellbeing benefits
- At least 14 weeks’ gender‑neutral parental leave
Position Requirements
10+ Years
work experience
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