Research Associate, Clinical Research, Research Scientist

Ask Bio Inc., a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life‑saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular, and metabolic disease indications with a clinical‑stage pipeline that includes investigational therapeutics for congestive heart failure, limb‑girdle muscular dystrophy, multiple system atrophy, Parkinson’s disease, and Pompe disease.

Ask Bio’s gene therapy platform includes Pro
10™, an industry‑leading proprietary cell line manufacturing process, and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, the company has generated hundreds of proprietary capsids and promoters, several of which have entered pre‑clinical and clinical testing.

Pioneering science to create transformative molecular medicines.

Lead innovative science and drive clinical outcomes to transform people’s lives.

• Advance innovative science by pushing boundaries.
• Bring transformative therapeutics to patients in need.
• Provide an environment for employees to reach their fullest potential.

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
• Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
• Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
• Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

The Research Associate I, Histotechnologist, will report to the Senior Scientist, Biodistribution Lead, and will participate in the development, validation and execution of histological assays, including immunohistochemistry, RNAscope/Base Scope, routine histology stains in support of pre‑clinical and clinical stage programs. This is an on‑site lab‑based position in Morrisville, NC and prior experience with tissue processing and immunohistochemistry is preferred. The ideal candidate would have knowledge of histology techniques.

Candidates may also have opportunities to learn different techniques for protein, DNA and RNA assessment on tissue sections.

This position is based in RTP, North Carolina and will report to a Senior Scientist.

• Perform manual and automated immunohistochemical staining.
• Perform manual and automated in situ hybridization (RNAscope/Base Scope) staining.
• Perform routine histological staining.
• Equipment maintenance.
• Maintain accurate records with Good Documentation Practices.
• Comply with established SOPs, established laboratory procedures and policies.
• Ensure lab areas are well organized, and supplies are available and safety protocols are followed.
• Perform routine histological procedures for FFPE and cryo samples to include tissue trimming, sample processing, embedding, and sectioning.
• High quality microscopy slide production for microscopic examination by a pathologist or investigator.

• Bachelor’s degree in biological sciences or related field.
• Basic Laboratory skills - Pipetting, reagent prep, lab documentation, and good laboratory practices.
• Basic histology experience, and cryo-sectioning/microtomy experience on cryostat/sliding microtome.

• Experience in routine histology.
• Experience in histological and immunohistochemical staining.
• Experience in in situ hybridization.
• HT or HTL certification or willingness to obtain the certification within 1 year of employment.
• Excellent manual dexterity, attention to detail, and the willingness to work in a team‑based…