Early Phase Research Nurse

Tennessee Oncology, one of the nation’s largest, community-based cancer care specialists, is home to one of the leading clinical trial networks in the country. Established 1976 in Nashville, Tennessee Oncology’s mission remains unchanged:
To provide access to high-quality cancer care and the expertise of clinical research for all patients, at convenient locations within their community and close to their home. Our growing network of physicians and locations is based on this mission. Tennessee Oncology is committed to advancing both the science of detection and targeted treatments, and to making these advances available to every patient.

We believe caring for cancer patients is a privilege.

We are looking for talented and highly-motivated individuals who demonstrate a natural desire to support the meaningful work of community oncologists and the patients we serve.

The Early Phase Clinical Research Nurse plays a critical role in the safe, compliant, and efficient conduct of early phase clinical trials at the Tennessee Oncology Greco Hainsworth Center for Research. This position provides comprehensive, patient-centered clinical care to research participants throughout the screening, treatment, and follow-up phases of clinical trials while working closely with the Principal Investigator (PI), delegated investigators, research team, and multidisciplinary clinical staff.

The Early Phase Clinical Research Nurse is responsible for coordinating and performing protocol-required clinical assessments and procedures, monitoring participants for treatment-related toxicities and adverse events, supporting investigational product administration, coordinating pharmacokinetic and other research specimen collections, providing participant education, and ensuring accurate and timely clinical and research documentation. The position requires a high level of clinical judgment, organization, attention to detail, and knowledge of Good Clinical Practice (GCP), regulatory requirements, and early phase research processes.

The nurse must be able to recognize changes in participant condition, promptly communicate safety concerns, and ensure protocol-required assessments and interventions are completed within specified time points and visit windows.

• Coordinate and provide comprehensive nursing care to participants enrolled in early phase oncology clinical trials from screening through treatment and long-term follow-up.
• Review study protocols, treatment plans, eligibility criteria, schedules of assessments, and safety requirements to ensure accurate execution of protocol-specific activities.
• Collaborate with the PI and delegated investigators to evaluate participant eligibility, clinical status, treatment readiness, and ongoing participation in clinical trials.
• Serves as the primary contact for assigned early phase research participants from informed consent through study completion.
• Screen and assess potential research participants in collaboration with the investigator and research team to determine eligibility according to protocol-specific inclusion and exclusion criteria.
• Facilitate the informed consent process and enroll eligible participants in accordance with protocol, regulatory, and institutional requirements.
• Provide comprehensive participant education regarding study requirements, treatment expectations, investigational products, potential risks and benefits, medication administration, required procedures, and when to contact the research team.
• Perform comprehensive and focused nursing assessments as appropriate to the study and participant's clinical condition.
• Obtain and document protocol-required vital signs, weight, height, oxygen saturation, pain assessments,…