Postdoctoral Fellow in Biophotonics and Multi-Omics Research in Pediatric Eosinophilic Esophagitis

Postdoctoral Fellow in Biophotonics and Multi-omics Research in Pediatric Eosinophilic Esophagitis

Department Pediatric Gastroenterology

Girish Hiremath, MD MPH

Full-time

Vanderbilt University Medical Center, Nashville

The Pediatric Eosinophilic Gastrointestinal Diseases Program at Vanderbilt University Medical Center is an NIH-funded, multidisciplinary, translational research group focused on addressing key diagnostic and prognostic gaps in eosinophilic esophagitis (EoE) - a chronic and progressive allergic condition of the esophagus affecting approximately 1 in 700 people in the United States and carrying an estimated $3 billion annual economic burden. Our work lies at the intersection of biophotonics, molecular biology, and clinical gastroenterology.

Specifically, we are leveraging and integrating Raman spectroscopy (RS), stimulated Raman scattering (SRS) microscopy, second-harmonic generation (SHG) microscopy, transcriptomics, and machine learning to develop novel multimodal markers of disease activity and complications, and treatment response. The program operates in close collaboration with the Vanderbilt Biophotonics Center, spearheaded by Dr. Anita Mahadevan-Jansen and supported by active NIH funding.

We are seeking a highly motivated Postdoctoral Fellow to join a rigorously designed NIH-supported research program. This is an exceptional opportunity for a scientist seeking hands-on experience spanning optical spectroscopy and imaging, molecular biology, and computational multi-omics data integration in a clinically embedded translational research environment, with direct access to patient biospecimens, state-of-the-art instrumentation (including exceptional support from Vanderbilt cores), and a supportive, high-caliber mentorship.

We welcome self-driven and detail-oriented applicants capable of working effectively within a multidisciplinary team consisting of clinicians, engineers, molecular biologists, data scientists, and biostatisticians from either of the following backgrounds:
Biophotonics-trained candidates (optics, biomedical engineering, or a related field) with deep interest in extending their skills to transcriptomics, multi-omics integration, and clinical translational research; or Cell/molecular biology-trained candidates with strong wet-lab and bioinformatics skills, a strong foundation in label-free optical imaging techniques (Raman spectroscopy, SRS, SHG).