Senior Medical Director, Radiopharmaceutical Imaging; RPI

Life at BMS At Rayze Bio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, Rayze Bio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer.

Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about Rayze Bio:

• Define and own the diagnostic imaging portfolio strategy and target product profiles for nominated candidates, incorporating competitive intelligence and evolving standards of care.
• Serve as imaging Clinical Development lead, providing medical and scientific direction across programs and ensuring robust, decision-oriented development plans.
• Lead and influence cross‑functional matrix teams and external partners (investigators, academic collaborators, CROs, central readers) to design and execute early‑and late‑phase imaging studies.
• Accountable for protocol concepts and critical document content, including protocols, investigator brochures, SAP inputs, clinical study reports, and key regulatory and medical communications.
• Performs medical monitoring and data review activities in support of clinical studies
• Provide medical oversight for trial conduct, including eligibility/risk assessments, safety review, medical monitoring strategy, and escalation pathways in collaboration with Drug Safety/Pharmacovigilance.
• Lead governance for imaging programs, including data review activities and Independent Data Monitoring Committees (IDMCs)/Data Monitoring Committees (DMCs) as applicable.
• Translate findings from research, translational, and nonclinical studies into imaging development opportunities and decision points; synthesize evidence to drive go/no‑go recommendations.
• Drive strategic regulatory engagement as clinical lead for health authority interactions, including briefing package strategy, participation in meetings, and representation of clinical rationale.
• Establish and maintain strong relationships with clinical investigators and key opinion leaders; represent Rayze Bio externally at scientific meetings and advisory boards as needed.
• Work closely with CROs and vendors in the execution of clinical trials for radiopharmaceutical imaging agents
• Participate in health authority interactions, preparation of briefing books, HA requests for information and regulatory filings.
• Partner with Medical Affairs and Commercial to develop the evidence‑generation strategy and lifecycle plans for radiopharmaceutical imaging within the broader Rayze Bio portfolio.
• Contribute to resource planning, timeline and budget management, risk mitigation/contingency planning, and vendor oversight to ensure delivery against milestones.
• Leverages AI to drive program, portfolio, or functional performance through prioritization and scaled adoption.
• Willing to travel approximately 30% of the time.
• Evening and weekend work may be required.

• MD (or equivalent) with 8+ years of pharmaceutical/biotech and/or relevant academic clinical experience, including substantial experience in oncology diagnostic development and/or radiopharmaceutical imaging agent development through regulatory submissions
• Demonstrated leadership in clinical development with increasing levels of responsibility, including leading cross‑functional teams and driving strategy through key development decisions.
• Experience across…