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VP, Data Architecture & Engineering

Job in Nashville, Davidson County, Tennessee, 37247, USA
Listing for: Astera Cancer Care
Full Time position
Listed on 2026-08-30
Job specializations:
  • Software Development
    AI Engineer (Applied/Software), Data Engineering
Salary/Wage Range or Industry Benchmark: 180000 - 280000 USD Yearly USD 180000.00 280000.00 YEAR
Job Description & How to Apply Below

Why join us?

One Oncology is positioning community oncologists to drive the future of medical care through a patient-centric, physician-driven, and technology-powered model to help improve the lives of everyone living with cancer and other diseases. Our team is bringing together leaders to the market place to help drive One Oncology's mission and vision. This is an exciting time to join One Oncology. Our values-driven culture reflects our startup enthusiasm supported by industry leaders in oncology, urology, technology, and finance.

We are looking for talented and highly-motivated individuals who demonstrate a natural desire to improve and build new processes that support the meaningful work of independent physicians and the patients they serve.

Job Description:

The Vice President, Data Architecture & Engineering reports directly to the Chief Technology Officer (CTO) and serves as the senior leader responsible for One Oncology's software, data, and integration engineering strategy, execution, and operational excellence. This role provides strategic leadership for all functions within engineering, establishing a unified engineering vision and operating model that delivers secure, scalable, reliable, and interoperable technology solutions.

The VP partners closely with Data & Analytics, Security, Infrastructure, and strategic business leaders to accelerate innovation, advance AI-enabled capabilities, and deliver technology that supports One Oncology's operational, and business objectives. This is a hybrid role based in Nashville, TN. Exceptional remote candidates may also be considered.

Responsibilities:
  • Define and execute the enterprise engineering strategy and multi-year technology roadmap aligned with One Oncology's business, clinical, data, and product priorities.
  • Lead Data Engineering, Integration Engineering, platform, and architecture functions with clear accountability across the engineering organization.
  • Lead Software Engineering team in support of creating AI and Data Products
  • Lead and develop engineering directors, managers, architects, and technical leaders; strengthen succession planning, career paths, and leadership capability.
  • Partner with business stakeholders to translate strategic priorities into executable engineering plans, investments, and delivery commitments.
  • Own engineering execution across product and platform portfolios, improving delivery predictability, quality, scalability, reliability, and time to value.
  • Establish engineering standards for architecture, software development, testing, deployment, observability, documentation, security, and production support.
  • Drive cloud-native engineering practices including APIs, microservices, Dev Ops, CI/CD, automated testing, and site reliability practices.
  • Provide executive leadership for enterprise data engineering and data platforms supporting analytics, reporting, AI/ML, interoperability, and operational workloads.
  • Lead enterprise integration and interoperability strategy across EHRs, practice management systems, third-party platforms, APIs, HL7, FHIR, and related standards.
  • Establish engineering KPIs and operating metrics for quality, reliability, delivery performance, technical health, and organizational effectiveness.
  • Lead engineering investment planning, vendor strategy, and resource allocation while balancing innovation, cost, and operational performance.
  • Communicate strategy, progress, risks, dependencies, and investment needs to executives and cross-functional stakeholders while building an inclusive, accountable, high-performing engineering culture.
  • Develop and execute the engineering strategy for artificial intelligence (AI), machine learning (ML), and intelligent automation, aligning initiatives with business objectives and product strategy.
  • Identify, evaluate, and drive adoption of AI technologies to improve software development, operational efficiency, clinical workflows, and customer experiences.
  • Establish governance, security, and responsible AI practices to ensure compliant, ethical, and scalable implementation of AI solutions.
  • Partner with Product, Data, and Analytics leadership to deliver AI-enabled capabilities leveraging enterprise data assets.
  • Champion the use of AI-assisted engineering tools to improve developer productivity, software quality, and delivery velocity.
  • Additional responsibilities as assigned to help drive our mission of improving the lives of everyone living with cancer.
Qualifications:
  • Required:

    Bachelor's degree in Computer Science, Engineering, Information Technology, or a related field, or equivalent relevant experience.
  • Master's degree preferred.
  • 12+ years of progressive experience in software, data, platform, or related engineering disciplines in enterprise-scale technology environments.
  • 7+ years of engineering leadership experience with demonstrated success leading leaders and multi-disciplinary engineering teams through multiple layers of management.
  • Experience leading software engineering, data engineering,…
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