Associate Director, Medical Training; Pipeline

Who We Are:

Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.

We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026.

Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial.

In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN
1701 (targeting Nav
1.7) and XEN
1120 (targeting Kv7), which are important pain targets. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

We are seeking an Associate Director, Medical Training (Pipeline) to lead the strategy, development, and execution of pipeline training across our therapeutic areas (including epilepsy, major depressive disorder, and bipolar depression) and broader neuroscience portfolio. This role will build scalable, audience-tailored training programs and modules to ensure internal teams are confident, consistent, and compliant in how we communicate science, evidence, and unmet need.

To be successful in this role, you will bring strong scientific acumen and a passion for adult learning, translating complex clinical and mechanistic concepts into clear, practical learning experiences. You will partner closely with Medical Directors and cross‑functional stakeholders to develop and maintain FAQs, core talking points, objection‑handling resources, and other enablement tools, and you will lead onboarding and ongoing medical training for new hires.

Reporting directly to the Executive Director, Medical Affairs, you will work within a multidisciplinary team, interfacing with Clinical Development, Scientific Communications, Commercial, Legal, Regulatory, and Compliance to ensure training content is accurate, aligned, and delivered with high quality.

This position is based out of Boston, MA, USA in our Needham office. We will consider remote locations for exceptional candidates. If in the Boston area, we require a minimum of 2 days per week in the office.

• Pipeline Training Strategy: Own the end-to-end training strategy for pipeline and disease‑state education (e.g., epilepsy, MDD, bipolar depression), ensuring content and curricula align to program milestones, evidence generation, and evolving scientific communications.
• Training Module Development: Design and develop engaging training modules for different audiences and use‑cases (field medical, sales, congress teams, cross‑functional partners), incorporating adult learning principles, knowledge checks, and practical application exercises.
• Onboarding & Role‑Based Curricula: Lead medical/scientific onboarding for new hires who require medical…