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Associate Director​/Director, Commercial Data Management

Job in Needham, Norfolk County, Massachusetts, 02492, USA
Listing for: Xenon Pharmaceuticals Inc.
Full Time position
Listed on 2026-07-26
Job specializations:
  • IT/Tech
    Data Analyst, Information Security & Data Protection, Business Systems & Technology Analysis, Data Science Manager
Salary/Wage Range or Industry Benchmark: 140000 - 200000 USD Yearly USD 140000.00 200000.00 YEAR
Job Description & How to Apply Below

Who We Are:

Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.

What We Do:

We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026.

Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial.

In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN
1701 (targeting Nav
1.7) and XEN
1120 (targeting Kv7), which are important pain targets. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

About the Role:

We are seeking an Associate Director / Director, Commercial Data Management, to help build and operate a trusted, governed, analytics-ready commercial data ecosystem in support of Xenon’s first anticipated product launch in epilepsy.

This role will serve as a key commercial business owner for commercial data management, master data management, data quality, data governance operations, reporting-ready data, and commercial data partner coordination. The role will ensure Xenon’s commercial data assets are accurate, timely, standardized, well-governed, and usable for launch performance measurement, field execution, targeting, segmentation, patient journey analytics, market access reporting, omnichannel measurement, and executive decision-making.

The role will also ensure Xenon’s commercial data foundation is structured, governed, and sufficiently high quality to support future AI/ML-enabled capabilities, including predictive analytics, dynamic segmentation, next-best-action, automated insight generation, and launch performance optimization. Key partnerships for this role will span the entire Xenon commercial organization, including Analytics, Sales & Field Effectiveness, Market Access, and IT, as well as core vendor partnerships to manage the Commercial Data Ecosystem.

This position reports to the Senior Director, Data Strategy, Operations, Analytics & Reporting and will be based out of Boston, MA, USA in our Needham office. We will consider remote locations for exceptional candidates. The level of the position will be commensurate with the candidate’s education and industry experience. Hybrid positions require a minimum of two onsite days per week.

RESPONSIBILITIES:
Commercial Data Management & Operating Model
  • Collaborate with internal and external partners on developing and operationalizing Xenon’s commercial data ecosystem across pre-launch, launch, and post-launch phases
  • Manage and define how commercial data will be governed, documented, validated, accessed, escalated, and used across the organization
  • Serve as the primary commercial business partner managing Xenon’s core data service partners (e.g. CDW, Data…
Position Requirements
10+ Years work experience
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