Scientist I, Imaging and Pharmacology

What can we offer you? Apart from job satisfaction, we can offer you:

• HEALTH Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)
• YOURSELF Paid time off policy including holidays and sick time
• Internal growth and development programs & trainings
• WEALTH 401(k) program, life & accident insurance and disability insurance

We are seeking a motivated and skilled Scientist I to support our invivo imaging studies using small animal models. This role is central to our preclinical research team and involves hands‑on work with nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI). The successful candidate will play a key role in project leadership, with the opportunity to oversee staff and lab spaces.

They will also provide technical support across a range of in vivo disease models, perform dosing and surgical procedures, and contribute to team leadership by mentoring junior staff. This position offers an exciting opportunity to evolve into a strategic leadership role within a fast‑paced, collaborative research environment. Whether leading a small team or contributing as a senior individual contributor, you’ll have the autonomy to drive research excellence and help shape the future of preclinical imaging studies.

• Team Leadership & Staff Development
  • Lead or support day-to-day activities within the invivo team, ensuring alignment with project timelines and goals.
  • May oversee and develop junior staff (2-4 members) provide training and technical guidance as needed.
  • Contribute to the management and optimization of laboratory space, including equipment and supply maintenance.
  • Develop, write and enforce laboratory‑specific standard operating procedures (SOP’s)
  • Evaluate study protocols and collaborate with Discovery Research teams during protocol development.
  • Liaise with IACUC and internal stakeholders to ensure compliance with animal use protocols (AUP’s)
  • Lead onboarding and integration of new team members.
• Study Support & Execution
  • Participate in protocol development and review with Discovery Research and cross‑functional teams.
  • Assist in coordinating study scheduling and establish timelines for protocol execution.
  • Execute a wide range of study types including:
    • Efficacy, biodistribution, pharmacokinetics, toxicokinetic, and xenograft models.
  • Perform dosing and surgical procedures such as:
    • IV, IP, SC, IM, PO administrations
    • Perfusion, tissue resection, microdissection
    • Biological sampling (blood, CSF, organs)
    • Survival surgery and CNS administration (preferred but not required)
  • Assist in image acquisition (PET, SPECT, CT, MRI) and related procedures.
  • Handle radioactive and BSL2 materials, including sample processing, gamma counting, and proper waste disposal.
  • Ensure strict adherence to laboratory SOPs and regulatory guidelines (IACUC, radiation safety, lab safety).
  • Ensure accurate data collection, analysis and reporting.
  • Maintain complete and clear laboratory records.
  • Monitor and report on animal health in collaboration with attending veterinarian.
  • Represent in vivo operations in meetings and cross‑functional communications.

• Some understanding of biology, pharmacology, or small animal imaging in the context of pharmaceutical research
• Ability to multi-task
• Comfort with various computer operating systems and programs
• Strong written and oral communication skills
• Occasional weekend and after‑hours work as needed
• Ability to lift 50 pounds

• Strong proficiency in IV dosing and minor surgical procedures
• Microdissection of specific tissues (e.g., lymph nodes, brain sections)
• Hands‑on experience in a preclinical imaging environment

• Bachelor’s degree in Biology, Animal Science, or related field, with 7+ years of relevant in vivo research experience or higher degree with 5+ years of relevant in vivo research experience.
• Demonstrated experience mentoring laboratory staff.
• Competence with computer systems and laboratory data platforms.
• Ability to lift up to 50 pounds.
• Availability to work occasional weekends as required.

The annual base…