Sr. Manager Engineering; Facilities

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award‑winning culture is collaborative, innovative, and science‑based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this. Let’s change the world.

In this vital role, you will provide leadership for Facilities & Engineering operations supporting Amgen Ohio (AOH), a state‑of‑the‑art final drug product manufacturing facility. You will be responsible for the safe, reliable, compliant, and efficient operation of site utility, facility, and infrastructure systems that support commercial manufacturing operations.

Reporting to the Director of Facilities & Engineering, the Senior Manager will lead a team of engineers and technical professionals responsible for utility systems, sustainability initiatives, asset lifecycle management, and engineering support activities. The role will work closely with Reliability Engineering, Maintenance, Manufacturing, Quality, EHS, and Capital Projects to ensure site operational readiness and long‑term asset performance.

The Senior Manager will be a key leader in driving reliability, operational excellence, sustainability, inspection readiness, and continuous improvement across the AOH campus.

• Provide leadership, coaching, and technical direction to a team of Facilities & Engineering professionals responsible for plant utilities, HVAC, building automation systems, electrical distribution, refrigeration systems and facility infrastructure.
• Ensure safe, reliable, and compliant operation of utility and facility systems supporting commercial packaging manufacturing.
• Develop and implement engineering strategies that improve asset reliability, operational performance, and lifecycle sustainability.
• Partner closely with Reliability Engineering to drive asset performance, condition‑based monitoring, predictive maintenance strategies, and risk reduction initiatives.
• Serve as the engineering owner for critical utility and facility systems, ensuring robust lifecycle management and system performance.

• Lead initiatives to improve equipment reliability, system availability, and operational efficiency across site infrastructure.
• Utilize performance metrics and engineering data to identify opportunities for continuous improvement and risk mitigation.
• Drive root cause investigations and corrective actions for significant utility, facility, or infrastructure events.
• Support the development and implementation of reliability‑centered maintenance and asset management strategies.
• Foster a culture of operational excellence through Lean, Continuous Improvement, and problem‑solving methodologies.

• Ensure utility systems operate in accordance with cGMP, regulatory, safety, and environmental requirements.
• Maintain a state of inspection readiness and support internal audits, regulatory inspections, and partner visits.
• Ensure engineering documentation, procedures, change controls, deviations, CAPAs, and maintenance practices remain compliant and effective.
• Collaborate with Quality and Validation organizations to support qualification, requalification, and…