Senior Manager, Manufacturing Systems Engineering; ASRS

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Manager, Manufacturing Systems Engineering (ASRS)

What you will do

Let’s do this. Let’s change the world. In this role, you will lead the engineering team responsible for the performance, reliability, and continued development of Amgen Ohio’s automated warehouse systems. You will manage engineers, system owners, and technicians supporting the Automated Storage and Retrieval System (ASRS), Automated Guided Vehicles (AGVs), Auto Store, material handling equipment, warehouse control systems, and their interfaces with manufacturing lines and SAP Extended Warehouse Management (EWM).

This role operates within a dual-reporting model with AOH site Facilities & E&E leadership and Global Engineering Technical Authority (ETA), enabling strong site ownership while maintaining alignment with Amgen’s global automated warehouse engineering strategy, standards, and technical capabilities.

This is an engineering and operational leadership role responsible for both sustaining and advancing AOH’s automated warehouse capabilities
. You will establish the technical support model for a 24/7 manufacturing site, lead the response to system issues that affect material flow, and build a team capable of sustaining safe, compliant, reliable, and resilient operations. Beyond day-to-day operational support, you will lead continuous improvement, lifecycle management, system integration, and engineering support for expansion of the automated warehouse as site and business needs evolve.

Team leadership and operational support

• Lead, coach, and develop a team of engineers, system owners, and technicians. Set clear accountabilities, technical priorities, training plans, and performance expectations.
• Establish support coverage, escalation paths, and recovery procedures for automated warehouse systems in a 24/7 operation.
• Direct technical response to equipment failures, interface errors, and material flow interruptions. Coordinate troubleshooting and restoration with Warehouse Operations, Manufacturing, Maintenance, Digital Technology, Quality, and equipment vendors.
• Review system availability, transaction performance, recurring faults, and recovery times. Use performance data to prioritize corrective actions and reliability improvements.
• Ensure that system owners maintain current procedures, technical documentation, spare parts strategies, preventive maintenance requirements, and vendor support plans.
• Partner with Warehouse Operations to ensure automated systems support inbound, outbound, and manufacturing material flows. Resolve technical constraints affecting those flows.

System ownership and compliance

• Provide engineering oversight for…