Summer Intern Neuroscience

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC targeted protein degraders, that are designed to harness the body's own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and "undruggable" targets, the company has three investigational clinical-stage programs currently enrolling: ARV-102 for the treatment of patients with neurodegenerative disorders,ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas, and ARV-806, a KRAS G12D PROTAC for the treatment patients with solid tumors with KRAS G12D mutations.

On August 8th 2025, the U.S. Food and Drug Administration (FDA) accepted the New Drug Application (NDA) for vepdegestrant- an investigational, orally bioavailable PROTAC estrogen receptor degrader- for its use as a monotherapy in the treatment of adults with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-), ESR1-mutated advanced or metastatic breast cancer previously treated with endocrine-based therapy. In September 2025, Arvinas and Pfizer announced their plan to jointly select a third party for the out-licensing and commercialization of vepdegestrant.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#Team Arvinas is made up of passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company's values and mission - to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC protein degradation platform.

We're really excited about the work we're doing inside and outside of Arvinas, and think you will be, too. But don't just take our word for it - learn more about life at Arvinas and what employees have to say.

For more information, please visit

Position Summary

We are looking for a motivated individual to work as a summer intern (May 19 to August 15) within Neuroscience. This position will be focused on development of cellular and biochemical assays to support one of our preclinical programs. Under the guidance of staff, the intern will implement basic scientific techniques at the bench, critically read, process, and present selected papers from the relevant scientific literature, and a summary of their work at an end-of-summer student colloquium.

This position reports to a Research Investigator or another member of the Neuroscience group.

This will be a full-time, on-site position located at our headquarters in New Haven, CT.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

* 75% lab work: conduct experiments and analytical assays involving cell culture, protein detection, or protein:ligand interactions.

* Execution of assays to query targeted protein degradation: western blots, ELISA, reporter assays, etc.

* Use of lab automation for compound handling.

* Learn protein degrader pharmacology and data analysis.

* Apply excellent organizational skills to maintain lab stocks and lab cleanliness.

* Maintain clear experimental records and communicate well with supervisor and other team members.

* Deliver critical data by following provided protocols and guidance.

Qualifications

* Motivated and productive individual with excellent communication skills who works effectively in a team setting.

* Prior lab experience is required.

* Experience with aseptic…