Accounting Manager

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States.

Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at and follow us on Linked In and X.

Axsome Therapeutics is seeking an Accounting Manager to help lead the Company's accounting operations, financial reporting, and close processes. This role will partner with stakeholders across the organization to ensure accurate, financial reporting, strengthen internal controls, and drive process improvements that support the Company's growth. This position reports to the Assistant Controller.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles

• Plan, direct, and coordinate all accounting functions
• Review existing processes and functions for automation, enhancements, and improvements, including ERP, Procure to Pay, and Order to Cash process/systems
• Manage the monthly and quarterly close process and the consolidation of all financial data necessary for an accurate financial statement results and reporting
• Assist with the processes for budgets and forecasting, and preparation of variance analysis of budgets/forecast to actuals
• Support the financial reporting process for all SEC filings (10-Q, 10-K, Proxy) as well as review of external communications, including press releases, earnings releases, prepared remarks, and corporate deck
• Research, document, and provide support for accounting positions and technical accounting memos under US GAAP
• Coordinate quarterly reviews and annual audits with external auditors
• Assist and coordinate tax compliance tasks with external tax accountants, including providing required information for periodic tax reporting, and annual tax returns for federal, state, and local governments, international countries, and reviewing supporting tax schedules and filings
• Participate in the preparation and documentation of SOX narratives, development of control evidence expectations, detailed SOX testing plans and reviewing test guidance/scripts for completeness and accuracy
• Support with planning, facilitate, and provide guidance with management’s execution and verification that the SOX assessment of internal controls over financial reporting is performed in accordance with the Company’s control assessment approach
• Manage equity plan administration, including Black Scholes fair market value calculations with third party vendor, issuance of new grants, exercises, cancellations and forfeitures and work with third party vendor to process grants in online equity system
• Provide management with financial information to support decision-making process, including ad hoc reporting and management reports
• Provide leadership and the ability to influence key decisions, both as it pertain to the overall business needs and to the Accounting/Finance function

• Bachelor’s degree in accounting/finance
• Certified Public Accountant
• 6+ years of progressive accounting experience in the biotech industry or Big 4 accounting firms
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

• Excellent interpersonal, verbal, and written communication…