Senior Director, Commercial Strategy

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology companydedicatedto unlocking urgently needed new treatment options in mental health care.

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP
360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP
360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD.

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP
360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing.

- Compass Pathways

Job overview:

The Senior Director, Commercial Strategy leads integrated launch planning for COMP
360 in TRD, coordinating cross-functional activities across Commercial and key partner functions to ensure launch readiness. This role drives governance, execution, and visibility across milestones, risks, and dependencies to support a compliant and effective launch. This role is also future-focused, identifying opportunities for additional indications, studies, and growth for COMP
360 and the organization.

Location: Hybrid in our Jersey City office or remote in the United States.

Reports to
:
Chief Commercial Officer.

Roles and responsibilities (Include but are not limited to):

• Act as a “Chief of Staff” for Commercial Strategy
• Own the integrated launch plan for COMP
  360 in TRD, including critical path milestones, interdependencies, deliverables, assumptions, and key decision points
• Lead cross-functional launch governance, establishing operating rhythms, meeting cadences, status reporting, and escalation pathways that support effective execution
• Partner across Sales, Marketing, Market Access, Medical Affairs, Regulatory, Quality, IT, Finance, and Supply Chain to ensure launch activities are aligned, sequenced, and progressing against plan
• Identify program risks, gaps, and bottlenecks early, and drive mitigation plans with appropriate owners to maintain readiness timelines
• Build and maintain launch readiness frameworks, dashboards, and trackers that provide clear visibility to leadership on progress, risks, and resource needs
• Coordinate the development of core launch enablers, including field readiness plans, systems readiness, process documentation, training coordination, and compliance-related activities
• Support executive-level decision making by synthesizing complex cross-functional inputs into concise recommendations, trade-offs, and action plans
• Ensure strong collaboration with commercial operations and technology partners to align systems, reporting, analytics, and tools required for launch execution
• Manage external vendors and launch-related partners where applicable, ensuring timely delivery, clear accountability, and effective issue resolution
• Contribute to post-launch planning, transition readiness, and lessons-learned processes to support sustainable execution beyond initial launch milestones
• Strategy as it relates to additional indications, P3B/4 studies, RWE, etc.
• Future focused planning for future indications including PTSD
• Identify and explore other future opportunities for the company

Candidate Profile:

• Bachelor’s degree in Business, Life Sciences, Project Management, or a related field; advanced degree preferred
• Significant experience in pharmaceutical or biotech commercial launch, program management, or strategic operations roles, including experience leading complex, cross-functional initiatives
• Demonstrated success driving launch readiness or large-scale business-critical programs in regulated environments
• Strong project and program management capability, including…