GMP RNA Vaccine Manufacture Specialist

About Us:

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it.

MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe.

The Olayan Center for Cancer Vaccines,a cornerstone of MSK’s immuno-oncology transformation,launcheda new RNA Therapeutics Lab and is seeking a GMP RNA Manufacture Specialist to join from the ground up!

In this role, you willdirectlycontribute to the development of mRNA-based personalized cancer vaccines, supporting immune manufacturing, characterization, and innovation, helping accelerate the translation of innovative vaccines into clinical use.

• GMP manufacture RNA-based drug substance and drug product, from DNA template to final drug product.
• Onboard and maintain RNA manufacturing equipment to ensure proper and continuous activity.
• Collaborate with the upstream group and GMP analyst to implement process improvements and tech transfer new RNA technologies.
• Continue purification development efforts initially on tangential flow filtration, but also investigating other purification methods, including chromatography, magnetic bead separation, etc. Cross-train with GMP analyst for redundancy, validation and qualification.
• Agile problem-solving for rapid and compliant turnaround time to release RNA personalized medicines.
• Generate and maintain compliant SOP’s.

• Master’s degree in biochemistry, biomedical engineering, or a related field and at least 4 years of experience, or a bachelor’s degree with at least 7 years of experience.
• Ability to perform all aspects of RNA-LNP production, including DNA template production, in vitro transcription, tangential flow filtration, and LNP formulation
• Experience with performing and building up GMP operations
• Expert laboratory skills and the ability to handle diverse tasks in a GMP setting.

• Outstanding communication and self-awareness.
• Critical thinking and problem-solving to optimize efficiency.
• Adaptability and resilience to lead change and innovation.
• Collaboration and building trusting relationships.

• Location:
  
  NYC;
  Zuckerman Research Center
• Schedule:
  
  37.5 hours per week (onsite)
• Reporting to the Associate Director

Pay Range: $82,000.00 - $ FSLA Status:
Exempt

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.