Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

What if your hard-won expertise in clinical trial design and regulatory science could directly shape how AI reasons about medical evidence - influencing the next generation of biomedical AI systems used by researchers and clinicians worldwide? We're looking for a Principal Clinical Scientist to bring senior-level clinical and regulatory knowledge into cutting-edge AI development. You'll work with Alignerr - a team that partners with the world's leading AI research labs - to ensure that AI models handling clinical data meet the rigorous standards of real-world regulatory science.

This is a fully remote, flexible contract role. No AI background needed - just deep clinical expertise and a sharp eye for scientific quality.

• Organization:
  Alignerr
• Type:
  Hourly Contract
• Location:
  
  Remote
• Commitment: 10-40 hours/week

• Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systems
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations from agencies such as the FDA, EMA, or equivalent
• Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and evidence
• Flag errors, inconsistencies, and methodological gaps in AI-generated clinical content
• Work independently and asynchronously - fully on your own schedule

• Senior-level experience designing and reviewing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong background in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented - you hold clinical content to the highest standards
• Comfortable evaluating scientific reasoning and providing clear, structured written feedback
• No prior AI or tech experience required

• Experience with data annotation, data quality review, or evaluation systems
• Background in pharmacology, medical affairs, or clinical operations
• Familiarity with AI tools or scientific content evaluation workflows
• Experience spanning multiple therapeutic areas or regulatory jurisdictions

• Work directly on frontier AI systems that are shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible - work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-stakes expert work
• Collaborate with leading AI research teams on problems that matter
• Potential for ongoing work and contract extension as new projects launch