Molecular Laboratory Supervisor

Lighthouse Labs Services is seeking an experienced Clinical Laboratory Supervisor in Long Island City to oversee daily operations within a New York State Department of Health CLIA/CLEP clinical laboratory specializing in high-complexity infectious disease testing. The laboratory utilizes advanced molecular technologies, including NGS and PCR-based processes, LDT applications, and specialized techniques across clinical microbiology, molecular virology, mycology, bacteriology, and parasitology.

The Supervisor will provide day-to-day oversight of laboratory operations, workflow, quality, and personnel while ensuring testing is performed accurately, efficiently, and in accordance with CLIA, CLEP, and applicable regulatory requirements. This role will also provide technical guidance to staff, support troubleshooting and assay validation, oversee competency and training, and help ensure the laboratory maintains high standards of patient testing and turnaround time.

Working closely with the Chief Medical Officer, Chief Scientific Officer, and Clinical Laboratory Director, the Supervisor will help support the continued development and operation of the laboratory, including implementation and optimization of molecular testing methodologies and processes. The ideal candidate will bring strong technical expertise in molecular and infectious disease testing along with the leadership skills needed to guide a growing, specialized laboratory team.

Our client is a growing health technology organization focused on advancing infectious disease diagnostics and improving patient care. The organization combines innovative laboratory testing, molecular technologies, and data-driven approaches to develop diagnostic solutions for patients, clinicians, healthcare systems, and researchers.

• Supervise daily laboratory operations, workflow, staffing, and patient result reporting.
• Ensure testing meets established turnaround times, quality standards, and regulatory requirements.
• Supervise, train, mentor, and assist with hiring qualified laboratory staff.
• Oversee competency assessments, staff performance, and ongoing training.
• Ensure adequate on-site coverage based on laboratory workload, testing complexity, staffing, and operational needs.
• Monitor reagent and supply inventory and communicate needs to laboratory leadership.
• Collaborate with management and other department leaders to support overall laboratory operations.
• Participate in staff and management meetings.
• Recommend improvements to testing procedures, equipment utilization, and laboratory workflow.
• Perform other duties as assigned by laboratory leadership.

• Perform routine and complex molecular testing in accordance with established laboratory procedures.
• Handle and process clinical specimens, including urine, vaginal swabs, stool, blood, CSF, synovial fluid, and respiratory specimens related to infectious diseases.
• Perform accessioning, biobanking, nucleic acid extraction and quantification, PCR, and next-generation sequencing as applicable to the laboratory's testing menu.
• Perform manual and automated techniques for high-volume specimen processing.
• Operate, maintain, and troubleshoot laboratory instrumentation and LIS systems.
• Apply knowledge of testing methodologies and the clinical relevance of tests performed within the department.
• Assist with validation and implementation of new assays and methodologies.
• Perform scheduled preventive maintenance and maintain associated records.
• Perform quality control and proficiency testing, document results and corrective actions, and follow established procedures when QC requirements are not met.
• Recognize abnormal instrument or test performance and withhold patient results until issues are resolved.
• Communicate critical values according to established procedures and follow laboratory downtime procedures when the LIS is unavailable.
• Communicate clearly and professionally with coworkers and effectively demonstrate laboratory procedures.

• Bachelor's degree in the sciences or a related field with 4 years of experience in a clinical laboratory setting, OR a Master's degree in the sciences or a related field with 2 years of experience in a clinical laboratory setting.
• Licensed as a Clinical Laboratory Technologist in New York State.
• Knowledge of Clinical Laboratory Improvement Amendments (CLIA).
• ASCP certification is preferred but not required.
• Basic knowledge of computer fundamentals and experience with laboratory information systems.
• Experience with Qiagen extraction systems, Illumina sequencing platforms, and Integra liquid-handling robots is highly preferred.

• Supervisory experience in a clinical laboratory setting.
• Training in infectious diseases (bacteriology, virology, parasitology, and mycology) and molecular diagnostics.
• Prior experience supervising CLIA laboratory high-complexity testing.
• Experience with Qiagen extraction systems, Illumina…