Assistant or Associate Professor in Genomic Medicine Tenure Track

Division of Genomic Medicine, Department of Medicine and Institute for Genomic Health | Icahn School of Medicine at Mount Sinai | New York City

Lead the integration of genomics into everyday medicine

The Icahn School of Medicine at Mount Sinai is seeking exceptional Assistant or Associate Professor tenure-track faculty candidates who are talented physicians and/or physician-scientists who will develop and implement genomic medicine programs within the Division of Genomic Medicine (DGM), Department of Medicine, and the Institute for Genomic Health (IGH).

Genomic medicine has arrived. AI-enabled analysis of millions of sequenced genomes linked to real-world clinical data is transforming how we predict, prevent, diagnose, and treat disease. Mount Sinai is one of the few places in the world where that transformation is happening inside a health system, at population scale, in one of the most diverse patient communities. The successful candidate will work under the leadership of Dr.

Michael Murray, Chief of the Division of Genomic Medicine and Clinical Director of IGH, and Dr. Eimear Kenny, Founding Director of IGH.

Faculty enjoy full access to:

• The Genomic Screening Program and Genomic Health Clinic
  ; pioneering programs returning actionable genomic results to patients and embedding genomic and polygenic risk information in routine clinical care Department of Medicine's Genomic Health Clinic
• The Mount Sinai Million Health Discoveries Program
  ; launched in 2022 in partnership with the Regeneron Genetics Center, this landmark initiative is sequencing the genomes of one million racially and ethnically diverse Mount Sinai patients linked to their electronic health records, making it one of the largest and most diverse health-system-based sequencing efforts in the world.
• The Bio Me Biobank
  ; a pioneering EHR-linked germline DNA repository of more than 70,000 Mount Sinai patients, generating genomic discoveries since 2007.
• A state-of-the-art high-performance computing and AI ecosystem
  , including Mount Sinai's Scientific Computing and Data Science resources, the Data Ark, and the AIRMS secure AI research platform.
• Major NIH-funded consortia and clinical partnerships
  , including eMERGE and its Polygenic Risk Score Program, CSER, Clin Gen, TOPMed, GSP, PAGE, the Human Pangenome Reference Consortium, and the NIH All of Us Research Program. Clinically integrated across the Department of Medicine's Divisions to promote Genomic Implementation across Adult Primary and Specialty Care.

You will be embedded in a fast-paced, highly collaborative team of clinician-scientists, data scientists, genetic counselors, health system researchers, and disease-area experts who share a single goal: translating large-scale genomic data into new paradigms for human health.

Current arenas of IGH and DGM research include mining deep genomic databases with machine learning and AI; basic and discovery science spanning population and statistical genetics, variant interpretation, structural variation, host genomics of infectious disease, and the genetics of complex and psychiatric traits; accelerating clinical genomic and polygenic risk prediction; running clinical trials that integrate genomic information and novel technology into routine care;

and advancing health equity by building the resources, knowledge, and best practices needed to bring genomic medicine to diverse and underserved populations.

The successful candidate will be supported in developing new clinical collaborations for adult care and helping to build the rapidly expanding set of clinal collaborations for diagnostic testing and elective screening. We are building models for implementing genomic medicine programs and lead an independent research program leveraging cutting‑edge health systems data. Research programs may span, but are not limited to:

• Translating genomic information into novel therapies
• Genomic and polygenic risk prediction for human diseases and preventive health
• Genomic medicine implementation, including clinical trials, population screening, and implementation science in diverse populations
• Clinical, basic, or translational research in human genetics and genomics

This will be a faculty appointment at a rank commensurate with experience, with a primary appointment in IGH and the Division of Genomic Medicine, Department of Medicine, consistently ranked among the top departments nationally for NIH funding. Tenure-track candidates are…