Principal Scientist, Oncology

Who we are…

Nuvation Bio is a biopharmaceutical company tackling some of the greatest unmet needs in oncology by developing differentiated and novel therapeutic candidates. Our vision is to significantly change the practice of oncology by developing medicines that provide truly meaningful improvements in quality of life and survival for people with cancer.

Nuvation Bio is looking for a highly motivated and productive Principal Scientist to join our Research Department supporting our drug discovery and development programs. The Principal Scientist will contribute to research for multiple oncology discovery programs. They will initiate, direct, and manage external and internal experimental studies that are critical to advancement of programs, informing corporate strategy, and working to serve the unmet medical needs in oncology.

• Support the research strategy for multiple oncology programs by designing and executing critical and relevant experimental studies that further the understanding of Nuvation Bio compounds
• Responsible for study planning, protocol design, study execution, and data analysis of pharmacology and mechanism of action studies
• Manage outsourced studies with external vendors/CROs/academic collaborators
• Support medicinal chemists by providing data critical to understand SAR/biochemical characterization of early-stage programs
• Work cross-functionally with members of the broader research team and effectively collaborate with a fully integrated team to facilitate the success of Nuvation projects
• Build our reputation in the scientific community with conference presentations and publications
• All other duties as assigned

• PhD in relevant biological discipline with a minimum of 5+ years’ experience preferred, or MS with 7+ years, Bachelor’s degree with 10+ years of relevant pharmaceutical industry experience in a fast-paced environment
• Demonstrated and broad expertise in cancer cell biology with knowledge of relevant experimental techniques, including in vitro and in vivo oncology model systems
• Demonstrated expertise in the evaluation and development of small molecules
• Strong track record in oncology demonstrating knowledge of multiple fields of biology, reflected in multiple successful projects and publications 1
• Exceptional problem solving, analytical thinking, and strategic skills
• Excellent written and verbal communication skills with the proven ability to work effectively as a member of a multidisciplinary team

• Problem-Solver - As an action-oriented self-starter, you’re eager to apply your expertise in diagnosing inefficiencies, determining root causes, and recommending solutions to complex challenges.
• Personable - You establish and nurture highly effective relationships with colleagues and key stakeholders that support and advance project goals and objectives.
• Credible - Thorough understanding of clinical methodologies and providing sound analytical support, you quickly establish credibility as a reliable resource.
• Emotional intelligence, curiosity, and a knack to figure out a way to build something better
• Communication - Effectively listens, conveys, and receives ideas. Maintains a consistent flow of information. A strong presenter and effective communicator with the ability to influence stakeholders.
• Accountability - Acts with a clear sense of ownership - whether the task is in their role description. Holds yourself and others accountable to execute all tasks at hand through seen and unforeseen circumstances with high quality and integrity.
• Adaptability - Can manage in an environment of ambiguity. Embraces the change of a new system, process, technology, or idea in the organization. You could reassess priorities, alter goals and take risks.

• Competitive Base Salary, Bonus, and Equity Plans
• Unlimited Vacation and 10 Sick Days Annually
• Excellent Medical, Dental, and Vision Coverage
• 401K with Company Matching
• and much more!

The base pay offered will take into account internal equity and also may vary depending on the candidate’s job-related knowledge,…