Senior Director, Commercial Strategy & Operations

Senior Director, Commercial Strategy & Operations

Updated: July 9, 2026
Location: Manhattan, NY, United States
Job :16937-OTHLOC-CGdw Yfw7

This position serves as a pivotal strategic advisor and operational leader, reporting to the Syneos Health Senior Vice President while working in close collaboration with the customer's Vice President, Head of Sales. The core responsibility is to act as a trusted partner who translates the customer's strategy into flawless execution, driving organizational effectiveness and alignment across Commercial functions, and ensuring the timely delivery of all strategic priorities.

In this role you will be accountable for the development, coordination, and measurement of strategic commercial initiatives, which impact the overall effectiveness of the organization, including incentive programs, POA execution, performance management, productivity analysis, and monitoring budget/expenses.

The ideal candidate possesses a strong background in pharmaceutical industry strategy combined with proven product launch expertise. Success in this role requires a leader with exceptional project management capabilities, strong business acumen, prior sales leadership experience and excellent communication skills. They must have a demonstrated ability to manage relationships effectively and assist with guiding teams through the complexities of go-to-market strategies, from planning and risk mitigation to post-launch analysis.

Essential Requirements:
Strategic Planning & Business Execution

• Partner with Commercial Leadership to develop, execute, and monitor short- and long-term commercial strategies.
• Drive annual strategic planning, business reviews, launch readiness assessments, and operating plan development.
• Monitor progress against key commercial priorities, identifying risks, opportunities, and mitigation plans.
• Ensure alignment of resources, investments, and organizational priorities with business objectives.
• Serve as a trusted advisor to the VP of Sales and Commercial Leadership Team.
• Prepare executive presentations, business reviews, board materials, and strategic recommendations.
• Lead development of leadership meeting agendas, action tracking, and decision governance.
• Support executive communications and change management initiatives.

Cross-Functional Leadership

• Coordinate activities across Sales, Marketing, Market Access, Operations, Medical Affairs, Finance, HR, and Analytics.
• Facilitate collaboration and alignment on critical initiatives including product launches, organizational transformations, and growth strategies.
• Remove barriers to execution and resolve cross-functional issues impacting performance.

Commercial Operations & Organizational Effectiveness

• Establish processes that improve decision-making, accountability, and operational efficiency.
• Lead commercial governance processes, including business reviews and performance management cadence.
• Drive implementation of key initiatives and organizational priorities.
• Develop dashboards and performance metrics to monitor commercial success.
• Lead high-priority strategic initiatives from concept through implementation.
• Manage commercial project portfolios to ensure milestones, timelines, and deliverables are achieved.
• Coordinate launch planning activities for new products, indications, or business initiatives.
• Provide structured project management support for enterprise-wide programs.

Business Insights & Performance Management

• Analyze market, competition, and business performance trends.
• Synthesize complex information into actionable recommendations for leadership.
• Monitor commercial KPIs and performance against goals.

Culture & Organizational Development

• Foster a high-performance culture focused on accountability, collaboration, and continuous improvement.
• Drive employee engagement efforts and organizational communications.
• Operational Oversight:
  Support all aspects of the co-employment agreement to include interviewing and hiring, aligning strategic perspectives, coaching core behaviors, financial and administrative oversight, and all aspects of employment including performance management solutions.

Requirements:

• Education:
  
  Bachelor's degree in business,…