Research Technician - Rudensky Lab

Primary Work Address: 1275 York Avenue, New York, NY, 10021.

The Rudensky Lab at Memorial Sloan Kettering Cancer Center studies the molecular mechanisms governing the differentiation and function of lymphocytes and their role in immunity and tolerance. The lab’s work focuses on advancing understanding of immune regulation in health and disease, and operates in a dynamic, team‑oriented research environment dedicated to scientific discovery and translational impact.

The Research Technician will support ongoing research in immunology and cancer biology, working closely with lab members to execute experiments and maintain critical lab operations. The role offers exposure to a wide range of techniques and the opportunity to contribute to impactful research in a fast‑paced academic environment. Candidates should be self‑driven, collaborative, and motivated to advance cancer immunotherapy research. A 2‑ to 3‑year commitment is sought, with a preference for 3 years, to ensure continuity and meaningful contribution to ongoing projects.

• Perform general mouse husbandry, including genotyping, embryo preservation, rederivation, tissue sectioning, and transcardial perfusion.
• Manage complex mouse colonies, including maintaining census, ordering, and coordinating with collaborators.
• Support lab members with experiments using immunological and molecular biology techniques (imaging, flow cytometry, library preparation, PCR, cloning, etc.).
• Analyze and organize research data.
• Participate in lab meetings and review scientific literature.
• Assist with lab organization and general operational support.

Education & Experience

• Minimum of a bachelor’s degree in Biology or a related field.
• At least 1 year of hands‑on experience in a research laboratory.
• Experience working with animal models preferred.

Skills & Competencies

• Strong analytical and organizational skills.
• Ability to work independently and collaboratively.
• Willingness to learn complex techniques with general instruction.
• Demonstrated initiative and commitment to continuous learning.
• Interest in immunology, cancer biology, or related research areas.

• Strong affiliation with the MSKCC and Tri‑Institutional research community.
• Opportunities to attend seminars, conferences, and academic programming (as applicable).
• Exposure to cutting‑edge research in immunology and cancer biology.
• Collaborative, team‑oriented lab environment.
• Comprehensive benefits package.

Remaining in a normal seated or standing position for extended periods; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers (e.g., using a keyboard); communication skills using spoken word; ability to see and hear within normal parameters; ability to move about the workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).

Work may involve possible exposure to malodorous vapors, low‑dose radiation, contamination by toxic chemicals and acids, and presence of carcinogenic substances or other hazardous materials. Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Compensation Range: $19.24 (minimum) – $24.09 (midpoint) – $31.29 (maximum) per hour.

Pay Type:

Hourly. The salary is based on relevant job market data, candidate education, experience, knowledge, skills, and internal consistency.

HHMI is an Equal Opportunity Employer. Please use E‑Verify to confirm identity and employment eligibility. For more information about your rights as an applicant, please review the Family and Medical Leave Act (FMLA), Know Your Rights, and Employee Polygraph Protection Act (EPPA) posters.