Director Precision Medicine

The Precision Medicine group at Regeneron is responsible for designing, implementing, executing, analyzing, and interpreting the overarching clinical biomarker strategies for therapeutic candidates during clinical development. We are seeking to hire a hands‑on Precision Medicine Strategy Lead (PMSL) at the director level, with backgrounds in one or more therapeutic areas within the group. The role will independently oversee the development and execution of biomarker strategies across one or more therapeutic areas, with a preference in obesity/metabolism pharmaceutical development.

Scope includes Neurodegenerative Disorders, Cardiovascular Disease, Muscle and Metabolism Disorders, and Rare Genetic Diseases. In this highly matrixed role, the Lead will design, develop, communicate at senior levels, and operationally implement clinical biomarker strategies to support key programs in early and late‑stage drug development. Clinical technologies applied include biomarker assays, pharmacogenetic assessments, and other clinical and physiological testing devices.

• Enhancing our understanding of indications at a cellular and molecular level
• Conducting novel biomarker discovery, qualifying new biomarkers/approaches to expedite proof‑of‑concept for new drug candidates
• Optimizing label claims for later‑stage candidates, enabling personalized medicine principles to be applied when appropriate, in full development
• Focusing in therapeutic areas outside of Oncology, possessing broad understanding of disparate biomarker technologies, and deep experience in biomarker assay development and validation in clinical drug development
• Conducting in‑depth literature and technology reviews pertinent to assigned clinical development programs, identifying experts in multiple disease areas, navigating and supporting regulatory and logistical factors pertaining to clinical technologies

• Lead implementation of strategic vision for clinical biomarkers in one or more therapeutic areas across multiple programs and studies, enabling advances in target identification, indication selection, early indication of biological activity, and patient stratification/selection
• Serve as an individual contributor and senior‑level representative of Precision Medicine on development teams, delivering biomarker strategies from concept to execution, data delivery, and results interpretation
• Collaborate with Discovery Research and product development teams to incorporate precision medicine and biomarker strategies for molecules in discovery phases, influencing candidate molecule selection
• Represent Regeneron and partner with allied companies to develop and implement strategies for partnered alliances
• Collaborate with clinical operations teams to implement specific biomarker and exploratory sample collection and analyses in all relevant clinical studies
• Design, oversee, and manage internal and external research collaborations in clinical technologies and translational research
• Ensure clinical assays used in programs are fit‑for‑purpose, whether developed and validated internally or externally
• Collaborate with internal laboratories (Discovery Research, Molecular Profiling, Regeneron Genetics Center, DNA core, Bio Analysis, etc.) to develop validation plans for research assays
• Ensure timely delivery of results across programs, meeting expectations of program teams and senior management to increase precision medicine impact on global development
• Contribute to technical reports, study memos, clinical study reports, data reviews, scientific publications, and recommendations to development teams and management

• PhD and minimum 10 years of experience driving, managing, executing, and delivering results for complex multi‑functional projects
• Excellent communication, presentation, emotional intelligence, organizational, and team skills
• Strong track record in mentorship and development of direct reports
• Proven experience as a TA‑level lead for implementing strategic vision for clinical biomarkers across multiple programs and studies
• Ability to serve as an individual contributor and senior‑level representative of Precision Medicine on…