Senior Research Associate

Overview

[SENIOR] RESEARCH ASSOCIATE, BIOLOGY & IMMUNOLOGY at Aethon Therapeutics

New York City

Who We Are

Launched in 2023, Aethon Therapeutics is pioneering a new paradigm in immuno‑oncology: the deliberate creation of MHC-restricted neoantigens on the surface of cancer cells and their targeting with T cell-engaging multispecific antibodies. Through its proprietary Hap Immune™ platform, Aethon unites antibody-based immunotherapy and small molecule-based targeted therapy to expand the power and promise of both approaches for people living with cancer.

For more information, see  and see our latest publication.

Position Summary

We are seeking a highly skilled and motivated research associate or senior research associate to join our dynamic research team s presents a unique and thrilling opportunity to collaborate with multidisciplinary teams in a fast-paced and rapidly evolving biotechnology company. As a successful candidate, you will work closely with our accomplished R&D Scientists and Associates to design and develop groundbreaking molecules, research tools and assays in the field of cancer immunotherapy.

The ideal candidate will thrive in a collaborative, team-oriented environment, and consistently deliver high-quality data within tight timelines.

• Support the development and implementation of novel research tools, engineered cell lines, and cell-based assays using molecular biology and biochemical techniques.
• Independently maintain mammalian cell lines and perform cell-based assays, including flow cytometry, viability analysis, dose‑response studies, and immune cell functional assays.
• Engineer and characterize cell lines through transfection or lentiviral transduction to support target discovery, validation, and assay development.
• Communicate experimental plans and results to project teams, maintain meticulous electronic lab notebook documentation, and assist with general laboratory operations.

• B.S. or M.S. in Biology, Biochemistry, Bioengineering, Immunology, or a related field.
• 1–3 years industry, co-op, internship, or academic laboratory experience.
• Experience in standard mammalian cell culture techniques (thawing, culturing, freezing cell lines, vector design/cloning/sequencing, transfection, and viral transduction).
• Familiarity with techniques such as flow cytometry, cell viability assays, qPCR, ELISA, protein analysis, and basic DNA/RNA/protein handling.
• Experience with immune cell culture, T cell assays, cancer biology, cell sorting, Incucyte analysis, or mass spectrometry is a plus.
• Proficiency with scientific data analysis tools (e.g., Excel, Graph Pad Prism, Flow Jo).
• Strong communication skills, attention to detail, adaptability, and enthusiasm for hands-on laboratory research in a fast-paced startup environment.

We provide a vibrant startup environment where every employee contributes to our culture and science. We offer a generous total rewards plan that includes competitive salary, stock options, and benefits. The salary range for this role is $75,000 – $105,000 annually. Actual salaries depend on a variety of factors, including experience, specialty and education.

Applicants for this role must be authorized to work in the United States. U.S. work visa sponsorship is not available for this role, now or in the future.