Postdoctoral Fellow

Job Description

A Postdoctoral Fellowship is available beginning August 1st, 2026 to study the molecular and cellular mechanisms of HTLV-1-driven adult T-cell leukemia/lymphoma (ATLL). Being the only human cancer caused by a retrovirus, ATLL is a fatal disease with no effective therapy. Evidence is accumulating that ATLL diagnosed in North America and Japan may differ in their mutation patterns and in their anti-HTLV-1 host immune responses.

We use patient samples, cell lines, and novel animal models to investigate the roles played by selected ATLL-driver mutations. A particular focus is on altered epigenetic regulation and rewiring of the regulatory network governing normal CD4+ T cell development and differentiation. We also characterize functional interactions between transformed ATLL T cells and host immunity.

• Conduct discovery research on the mechanisms of HTLV-1-driven ATLL.
• Use patient samples, cell lines, and animal models to investigate selected driver mutations.
• Study epigenetic regulation and regulatory networks in CD4+ T cells.
• Characterize interactions between ATLL T cells and host immunity.

• Recent PhD or MD graduate with significant research experience.
• Proficiency in molecular biology techniques, including manipulation and analysis of gene expression in cultured and primary cells.
• Experience with cancer animal models.
• Knowledge of cellular immunology and/or computational skills desirable.
• First-authored publication(s) in peer-reviewed English-language journals demonstrating the capability to conduct discovery research.
• Ability to work independently, strong motivation for novel discoveries, and a strong work ethic.

Salary will be commensurate with experience.

More information about our work can be found at: https://(Use the "Apply for this Job" box below)./

Albert Einstein College of Medicine is an Equal Opportunity Employer.