Postdoctoral Associate in Pharmacology Yang lab

ostdoctoral Associate in Pharmacology in the Yang lab

Job Description:

The Postdoctoral Associate will investigate how NAD⁺ metabolism contributes to metabolic and age-related diseases, with a particular focus on diabetes, cardiovascular disease or aging. The successful candidate is expected to employ multidisciplinary approaches such as genetic engineering, multi-omics analyses, stable isotope tracing, and animal metabolic phenotyping to elucidate disease mechanisms and inform therapeutic development.

• Conduct the research independently and/or collaboratively with colleagues to ensure all experiments are appropriately conducted following Lab, Department, and College policies and procedures.
• Designing, organizing, and carrying out experiments using established protocols, and sometimes adapting to and designing new protocols.
• Collect, prepare, and analyze research data. This may include keeping a detailed notebook summarizing experiments and recording research data and/or maintaining a computer database of the research data.
• Tabulate data for presentations and use graphics and statistical software to analyze and present data.
• Participate in abstract and article preparation with the Principal Investigator, publish results in research journals, and present findings at conferences.
• Assist the Principal Investigator in applying for fellowship, grant, and scholarship support, as requested.
• Assume general responsibility for scientific operations of the laboratory, including training and supervising interns, students, and other laboratory personnel, as necessary.

• Doctoral degree (PhD or equivalent) in molecular biology, biochemistry, or a related field.
• Demonstrated research productivity through peer-reviewed, first-author publications.
• Strong commitment to a career in biomedical research.
• Ability to independently design and execute experiments, troubleshoot technical challenges, and adapt experimental protocols as needed.
• Strong interpersonal and collaborative skills, with the ability to work effectively in a multidisciplinary research environment.
• Excellent oral and written communication skills, with the ability to present research findings and contribute to scientific discussions.
• Strong background in animal physiology, molecular biology, and/or related biomedical research areas.
• Three letters of recommendation.

• Prior research experience in Type II diabetes, heart failure, or related metabolic and cardiovascular disease models.
• At least two years of hands‑on experience with mouse studies, including animal handling and minor surgical procedures.
• Experience in primary murine cell isolation, culture, and functional assays.
• Experience with gene editing approaches, such as CRISPR-based genome engineering or viral-mediated gene manipulation.
• Technical proficiency in key experimental techniques, including flow cytometry, confocal microscopy, immunostaining, Western blotting, qPCR, and mammalian cell culture.
• Experience with high-throughput data analysis and bioinformatics tools for multi-omic or large-scale datasets.

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