Senior Scientist- Metabolomics

We are seeking a Senior Scientist – Metabolomics to join a growing life sciences organization in New York. This is a hands-on laboratory position for a scientist with strong experience in LC-MS/MS, metabolomics,
lipidomics , or small-molecule analysis .

You will help develop and improve analytical methods, perform and analyze experiments, troubleshoot laboratory instrumentation, and support research projects from initial method development through final results . This is an excellent opportunity for an experienced analytical scientist who enjoys hands-on laboratory work, method development, and solving complex scientific problems

• Develop, optimize, and validate LC-MS/MS methods for metabolomics, lipidomics , and small-molecule analysis.
• Prepare and analyze biological samples using techniques such as protein precipitation, liquid-liquid extraction (LLE), and solid-phase extraction (SPE).
• Operate and troubleshoot LC and mass spectrometry systems , including triple quadrupole and high-resolution mass spectrometers.
• Analyze and interpret mass spectrometry data, including metabolite identification and small-molecule quantification.
• Support instrument maintenance, validation, and troubleshooting.
• Prepare SOPs, validation documentation, and technical reports.
• Work with other scientists and project teams to plan studies, solve technical challenges, and communicate results.
• Provide technical guidance and mentorship to junior scientists as needed.

• PhD in Analytical Chemistry, Biochemistry, Chemistry, Pharmaceutical Sciences, or a related life sciences field with 2+ years of relevant post-graduate experience , OR a Master's
  degree with 5+ years of relevant experience .
• Hands‑on experience with LC‑MS/MS and mass spectrometry instrumentation .
• Experience with metabolomics,
  lipidomics , metabolite analysis, or quantitative small‑molecule analysis .
• Experience developing, optimizing, or validating analytical methods.
• Familiarity with mass spectrometry platforms such as SCIEX QTRAP 6500,
  Thermo Q
  Exactive , triple quadrupole systems, or comparable instrumentation .
• Experience preparing biological samples for LC-MS analysis.
• Working knowledge of LC separation techniques such as reversed‑phase chromatography and/or HILIC.
• Ability to troubleshoot experiments and instrumentation and independently interpret scientific data.
• Strong documentation, communication, and project‑management skills.

Experience with
GLP environments, assay validation, SOP development, and regulated pharmaceutical or bioanalytical laboratory work is highly valued.

• Relocation assistance and visa sponsorship are available for qualified candidates.

Sirius Staffing is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or any other status protected by applicable law