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Head of Medicinal Chemistry — Structure-Driven Drug Design

Job in New York, New York County, New York, 10261, USA
Listing for: Proxima
Full Time position
Listed on 2026-08-30
Job specializations:
  • Science
    Drug Discovery
Salary/Wage Range or Industry Benchmark: 180000 - 260000 USD Yearly USD 180000.00 260000.00 YEAR
Job Description & How to Apply Below
Location: New York

Proxima in Boston is seeking a Senior Chemist to drive chemistry on our pipeline programs, owning compound design and synthesis from hit identification through lead optimization. You will work shoulder to shoulder with our Boston biology team and ML scientists to ensure designs are synthetic and scientifically meaningful.

You will test Neo-1 outputs for synthetic feasibility, design routes, manage CRO partners end to end, and guide DMTA cycles to optimize potency, selectivity, and develop ability

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