Research Associate, Research Scientist, Clinical Research

The drug discovery and development team at Protagonist Therapeutics is seeking a highly motivated Contract Research Associate for a hands‑on laboratory position supporting ongoing research programs. This individual will perform screening on cell‑based assays under the direction of project scientists and contribute to timely generation and analysis of high‑quality data. The role requires strong technical skills, attention to detail, and the ability to work both independently and collaboratively in a fast‑paced environment.

This is a contract position focused on experimental execution and data support for active discovery programs.

• Perform and support cell‑based reporter screening assays and in vitro biochemical assays, including but not limited to ELISA, MSD and flow cytometry‑based assays.
• Collect, analyze, summarize, and communicate experimental data to project teams in a timely manner
• Maintain cell lines and routine laboratory operations related to assigned projects
• Manage reagent and sample inventories and maintain accurate records and databases
• Ensure laboratory equipment, reagents, and procedures are maintained according to established SOPs and industry standards
• Assist in writing and updating technical documentation, including assay protocols and data reports
• Follow established SOPs and contribute to continuous improvement of laboratory workflows

• B.S. or M.S. in Cell Biology, Molecular Biology, Immunology, or a related scientific field
• 3 years of relevant industry laboratory experience with a B.S. or 1 year with an M.S.
• Hands‑on experience with the following techniques:
  • Cell‑based assays and routine cell culture
  • MSD, ELISA and flow cytometry
• Proficiency with data analysis and documentation tools such as Graph Pad Prism, flow cytometry software, and Microsoft Office
• Strong attention to detail with excellent organizational, documentation, and time management skills
• Ability to follow SOPs precisely and adapt quickly to new procedures and project needs
• Ability to manage multiple tasks and priorities simultaneously

The base pay range for this position at commencement of employment is expected to be between $95K and $105K / year; however, base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience.

Protagonist Therapeutics is a discovery through late‑stage development biopharmaceutical company. Two novel peptides, icotrokinra and rusfertide, derived from Protagonist's proprietary discovery platform are currently in advanced Phase 3 clinical development, with New Drug Application submissions to the FDA expected in 2025. Icotrokinra (JNJ‑2113) is a first‑in‑class investigational targeted oral peptide that selectively blocks the Interleukin‑23 receptor ("IL‑23R") which is licensed to Janssen Biotech, Inc.,

a Johnson & Johnson company. Following icotrokinra's joint discovery by Protagonist and Johnson & Johnson scientists pursuant to the companies' IL‑23R collaboration, Protagonist was primarily responsible for development of icotrokinra through Phase 1, with Johnson & Johnson assuming responsibility for development in Phase 2 and beyond. Rusfertide, a mimetic of the natural hormone hepcidin, is currently in Phase 3 development for the rare blood disorder polycythemia vera (PV).

Rusfertide is being co‑developed and will be co‑commercialized with Takeda Pharmaceuticals pursuant to a worldwide collaboration and license agreement entered into in 2024 under which the Company remains primarily responsible for development through NDA filing. The Company also has a number of pre‑clinical stage oral drug discovery programs addressing clinically and commercially validated targets, including the IL‑17 oral peptide antagonist PN‑881, an oral hepcidin program, and an oral obesity program.