Lead Image Chain Systems Engineer

The Lead Image Chain Systems Engineer (Detector Integration) is a senior technical leader responsible for advancing Hologic’s x‑ray imaging platforms through innovation in detector subsystems and full image chain optimization.

This role drives the exploration, development, improvement, and integration of x‑ray detectors and sensor architectures, delivering measurable system‑level performance improvements and new acquisition modes across mammography, DXA, and specimen imaging platforms.

You will operate as a hands‑on expert and mentor, setting technical direction, executing complex R&D programs, and collaborating cross‑functionally to deliver robust, compliant solutions aligned with Hologic’s technology roadmap. This role is located in Newark, DE.

At Hologic, we’re redefining what’s possible in diagnostic imaging—and we need your expertise to make it happen. As a Lead Image Chain Systems Engineer, you’ll be at the forefront of innovation, designing next‑generation imaging platforms that combine advanced x‑ray hardware with powerful image processing software. Your work will directly impact patient care by delivering crystal‑clear images with maximum safety and efficiency.

• Lead development, test, and integration of x‑ray detectors and sensor solutions across multiple product platforms
• Drive innovation in detector designs, readout schemes, and performance‑enhancing modes
• Lead end‑to‑end signal‑chain development, including analog front‑end, digitization, calibration, and dose management
• Evaluate and mature new detector technologies and architectures
• Support pre‑processing pipelines, from flat‑field optimization to advanced image‑quality enhancement
• Establish and execute image‑quality metrics and test methods
• Deliver system‑level performance improvements through signal processing and calibration techniques
• Guide alignment of detector technologies with platform system architectures
• Support prototyping, benchtop testing, and early‑stage system integration
• Lead initiatives while remaining hands‑on through design, bring‑up, validation, and technology transfer
• Collaborate cross‑functionally to deliver robust, compliant solutions in a regulated environment
• Support IP strategy, risk management, requirements, design reviews, and verification documentation

We are seeking a hands‑on senior systems engineer with deep expertise in x‑ray detectors and imaging systems, capable of translating technology innovation into clinically impactful imaging performance improvements.

• Ability to bridge hardware, physics, and software domains
• Passion for innovation in medical imaging technology
• Strong leadership combined with hands‑on execution
• Customer‑ and patient‑centered mindset

• Understanding of medical imaging systems, including x‑ray physics, x‑ray tubes, digital detectors, and basis of image processing algorithms
• Proficiency in detector signal‑chain design, encompassing x‑ray conversion materials, pixel sensor backplanes, analog front‑end amplifiers, digitization, timing, calibration, and noise modeling & management
• Practical experience with detector embedded HW/SW systems and readout schemes architectures, and performance optimization
• Knowledge of hardware/software interoperability and the design of scalable, modular technology platforms
• Experience with front‑end technology exploration, proof‑of‑concept development, and early‑stage system integration & validation
• Familiarity with regulatory standards for medical devices (IEC 60601, ISO 13485, FDA design controls) and risk management practices
• Experience with system engineering principles, requirements development, and integration of complex medical imaging systems
• Competence in technology transfer, documentation, and cross‑functional product development processes

• Strong system‑level problem‑solving and root cause analysis
• HW acumen and solid embedded and application SW skills
• Proficiency in Python, C++, MATLAB, or similar
• Ability to lead multidisciplinary technical projects
• Excellent communication and technical documentation skills
• Hands‑on experience with prototyping, validation, and performance optimization

• Demonstrates…