Upstream Manufacturing Associate

This role is focused on the execution of mammalian cell culture operations to support the manufacture of recombinant proteins for a portfolio of mammalian-derived biosimilars. The successful candidate will be involved in running engineering and clinical-scale batches within a cGMP manufacturing environment, working across bioreactor volumes ranging from 50L up to 2000L. A strong technical understanding of upstream processing, documentation, and GMP compliance is essential.

• Execute mammalian cell culture activities including seed expansion, inoculation, culture monitoring, and harvest using single-use bioreactors up to 2000L
• Prepare and operate equipment for media and buffer preparation, seed train activities, and clarification steps such as depth filtration
• Complete GMP batch records, logbooks, and associated documentation accurately and in real time
• Maintain strict aseptic practices and contamination control within classified cleanroom areas
• Support equipment and facility readiness, including cleaning, setup, and area turnover
• Adhere to cGMP, SOP, and EHS requirements at all times
• Participate in a shift-based manufacturing schedule, which may include nights or weekends on rotation

• Associate’s or Bachelor’s degree in Biotechnology, Biochemistry, or a related scientific discipline
• Typically 2–6+ years of experience in upstream biologics manufacturing (Associate II / III level or equivalent)
• Practical experience with bioreactors, seed train operations, and clarification processes
• Comfortable working in GMP cleanroom environments with full gowning requirements
• Highly reliable, detail-focused, and collaborative, with strong documentation discipline
• Ability to work effectively both independently and within a team environment
• Clear verbal and written communication skills with strong organisational ability
• Proficient in basic computer applications, including Word and Excel
• Solid understanding of GMP manufacturing documentation, batch record review, and audit readiness