VP, Head of Commercial Operations New Watertown, MA

Patients with adenoid cystic carcinoma (ACC) have waited decades for a treatment option. At Remix Therapeutics, we intend to change that. We are a clinical-stage biopharmaceutical company that has pioneered a new class of small molecule medicines targeting the RNA splicing machinery — correcting the disease-causing errors that drive ACC and other serious conditions at their source. REM-422 is our lead program, currently in clinical evaluation for ACC and AML/HR-MDS, and it is at a critical inflection point.

Remix is building the team to bring this novel molecule forward for patients.

Remix is seeking an experienced, strategic and hands-on Vice President, Head of Commercial Operations to build and lead the company's Commercial Operations and Business Insights function, initially focused on REM-422. This executive will be accountable for forecasting, market research and competitive intelligence; commercial data and analytics; CRM and field technology; sales operations; incentive compensation; performance reporting; and the external partner ecosystem required to support launch.

Reporting to the Chief Commercial Officer and partnering closely with the Head of Sales & Marketing, Head of Market Access, Finance, IT, Legal and Compliance, this leader will translate commercial strategy into disciplined operating plans, high-quality decisions and scalable execution. The successful candidate will pair strategic judgment with analytical depth and a willingness to work directly in the details - from patient-based forecasting and vendor selection to field force design, and dashboard development.

• Set and lead the enterprise commercial insights agenda, integrating primary and secondary market research, epidemiology, patient journey and treatment-flow analysis, market sizing, customer insights and competitive intelligence.
• Build, maintain and communicate patient-based forecasts for ACC and future indications; partner with Finance on revenue scenarios, long-range planning and sensitivity analyses.
• Translate clinical and regulatory outcomes, target product profile assumptions, biomarker prevalence, treatment patterns, market access dynamics and competitive developments into clear commercial implications.
• Develop a sequenced learning plan that addresses the highest-value uncertainties for indication prioritization, positioning, go-to-market design, field planning, access strategy and lifecycle management.
• Create compliant mechanisms to capture and synthesize insights from customers, field teams, patient services, payers, external experts and data sources, then convert those insights into decisions and action.
• Support portfolio strategy, business development and new-product planning through commercial opportunity assessments, analog analyses and scenario modeling.

• Develop a phase-appropriate commercial data and analytics roadmap that supports pre-launch decisions, launch execution and post-launch performance management.
• Select, integrate and govern data from market research, claims, specialty pharmacy and distribution, patient services, market access, CRM, finance and other sources to create a reliable commercial source of truth.
• Design and implement the commercial technology stack, including CRM, business intelligence and dashboarding, data integration, customer master data, affiliations and account hierarchies.
• Establish data governance, quality standards, access controls, privacy and compliance requirements, vendor service levels and documentation in partnership with IT, Legal and Compliance.
• Build decision-oriented dashboards and reporting for executive leadership and commercial teams, balancing leading indicators, launch-readiness metrics and business outcomes.
• Manage commercial data, analytics and technology partners, ensuring fit-for-purpose solutions, disciplined budgets, strong performance and scalable architecture.

• Lead field force sizing, structure, territory design, targeting, customer segmentation, call planning and workload analyses for a focused rare-oncology model.
• Build the field operations model, including CRM…