Development Manager

The Amyloidosis Research Consortium (ARC) is a 501c(3) nonprofit organization founded in 2015, harnessing the power of collaboration and innovation to advance science and both improve and extend the lives of those with Amyloidosis. We are dedicated to transforming the way research is being done and focus on what will have the most significant impact on improving the lives of amyloidosis patients.

We forge collaborations across industry, research, clinical care, and regulatory to address unmet needs and accelerate the discovery of new treatments. ARC empowers and supports patients by ensuring they have access to the best quality care and information. ARC now has a staff of 14 professionals, and a $4.5M budget.

Amyloidosis is a group of diseases where abnormal proteins build up in organs, causing progressive damage. In the U.S., approximately 3,800 new AL amyloidosis cases are diagnosed annually. However, ATTR amyloidosis affects far more people: over 100,000 Americans have the age‑related form, and 50,000 people worldwide have the inherited form. Studies show that roughly 13% of older heart‑failure patients actually have undiagnosed ATTR amyloidosis, meaning the true patient population is even larger.

As awareness and diagnosis improve, the community continues to grow.

Development Manager plays a key role in advancing ARC’s fundraising efforts by ensuring strong day‑to‑day execution across donor engagement, stewardship, and development operations. Reporting to the Director of Development, this role manages the systems, processes, and workflows that support an effective and scalable fundraising program.

Responsibilities span the full fundraising lifecycle, including campaign execution, donor communications, grant tracking and submissions, and data management and reporting. The Development Manager also serves as the primary administrator for Salesforce, ensuring data integrity, reporting accuracy, and effective workflow configuration. In addition, this role engages directly with emerging and mid‑level donors through personalized outreach and stewardship, helping to strengthen relationships and support long‑term growth of ARC’s donor base.

The ideal candidate is detail‑oriented and proactive, with the ability to manage multiple priorities in a collaborative, mission‑driven environment. This role is well‑suited for someone who enjoys building structure and process while contributing to relationship‑driven fundraising efforts.

• Serve as a primary point of contact for donor and constituent inquiries across email, web, and phone, building strong relationships through responsive, professional, and service‑oriented communication.
• Manage donor gift processing and ensure donor acknowledgement processes are timely and accurate. This role requires a weekly in‑person visit to ARC’s Newton, MA office to support donor check processing and donor correspondence activities.
• Prepare pipeline and portfolio reports, develop briefing materials for donor meetings, and provide analysis on donor engagement trends and giving patterns.
• Identify and escalate high‑potential donors to the Director of Development for personalized cultivation.
• Conduct prospect research on individual, foundation, and corporate donors to support fundraising and donor engagement strategies.
• Track restricted gifts, maintain accurate fundraising revenue data, and monitor progress toward fundraising goals.
• Partner with program teams to transition participants into development pipelines and identify opportunities for deeper engagement.

• Own the end‑to‑end operational execution of mid‑year and annual fundraising campaigns, including timelines, dependencies, communications, quality control, and ensure campaigns run smoothly from setup through completion.
• Develop and execute donor segmentation, list pulls, and automated workflows for direct mail and digital campaigns to support revenue, engagement, and donor conversion goals.
• Coordinate donor cultivation events and small gatherings, including logistics, invitations, and RSVP tracking.
• Prepare event‑related donor…