Scientific Director, ADC Chemistry

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.

To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.

Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life‑changing medicines to the world.

Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

The Scientific Director of ADC Chemistry will be a key scientific innovator and operational leader responsible for shaping and advancing the ADC Discovery portfolio. This role requires a creative and scientifically driven leader who can identify and originate new research opportunities, guide early‑stage discovery projects, and contribute to the development of our ADC Discovery strategy across the research organization. The successful candidate will manage a team of chemists, lead multidisciplinary project teams, and implement operational improvements that enable rapid exploration and execution of innovative ideas aligned with our organizational strategy and goals.

• Help deliver the next generation of ADC therapeutics. Promote a culture of innovation by integrating new ideas, targets, technologies and methodologies into the ADC Discovery organization.
• Provide leadership to multidisciplinary project teams focused on development of the next generation of ADCs. Leverage a collaborative mindset to oversee strategic project planning, operational execution across internal teams and partner lines, and clear communication of project achievements and risks.
• Manage a team of ADC chemists, fostering a collaborative and high‑performing work environment. Provide supportive coaching, professional development, and performance feedback to direct reports to increase employee engagement and impact.
• Support operational improvements within ADC Chemistry and across the ADC Discovery organization. Proactively identify opportunities to increase productivity and quality through optimization of workflows and introduction of best practices.
• Contribute to the strategic direction of the ADC Discovery organization and align ADC Chemistry initiatives with broader organizational goals.

• Ph.D. in Chemistry, Biochemistry, or a related scientific discipline, with 12+ years of experience in the pharmaceutical or biotechnology industry.
• Prior experience in ADC discovery with a focus on novel payload development is preferred. Candidates with extensive experience in small molecule modalities and interest in targeted drug delivery will also be considered.
• Demonstrated success in advancing innovative scientific projects and driving operational improvements.
• Ability to lead and develop high‑performing teams in a matrixed organization.
• Proven ability to manage direct reports for individual performance and career growth.
• Strong communication, interpersonal, and organizational skills.

• Last Day to Apply:
  March 9, 2026
• Relocation support available
• Work Location Assignment:
  On Premise

The annual base salary for this position ranges from $ to $. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share‑based long‑term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.

Benefits offered include a 401(k) plan with Pfizer matching contributions and an additional Pfizer retirement savings contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Compensation structures may vary by location.

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