Senior Manager, Clinical Project Management; Project Delivery

Senior Manager, Clinical Project Management (Project Delivery)

Bothell, Washington, United States

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA;

IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

The Senior Manager, Clinical Project Management (Clinical Project DeliveryCPD) provides hands-onoperationalmanagementfortheexecution ofone or moreof

Immunome’s clinical trials,supporting all aspects ofcross-functionalclinical trial delivery from planning and initiation throughcompletiontoensurestudies areexecutedon time, within budget,and in compliance with regulatory requirements and corporate objectives.

The Senior Manageractsas the primary point of accountability forstudy-level timelines,enrollment projections,budgets, and vendor performance for assigned trials.

The Senior Managermaysupportone or morestudiesand/or development programs under the guidance of an Associate Director or above.

Responsibilities

Clinical Project Delivery

• Lead cross - functional facilitation of clinical study teams through the trial lifecycle .
• Own study-level timeline development, tracking , and reporting for assigned trials.
• Develop and maintain enrollment graphs and dashboards, ensuring accuracy and timel y updates to inform decision-making .
• Monitor project delivery metrics ( timelines, milestones , enrollment, budget adherence, vendor KPIs) and ensure correcti ve action when studies are at risk.
• Facilitate or support cross-functional planning, execution, and delivery of assigned clinical trials on time, w ith in budget, and to quality standards.
• Help the clinical study team (CST) i dentify operational risks and implement mitigation strategies to ensure successful trial delivery.

Clinical Operations

• Champion a culture of accountability, collaboration, and continuous improvement.
• May contribute to functional and/or departmental initiatives.
• May mentor new or junior team members.
• Manage CRO and Central lab relationships and oversight for assigned studies .
• Initiate vendor identification, selection, contracting, and onboarding activities in support of Finance, Legal , and clinical study teams.
• M anage and m onitor vendor performance against contractual obligations, operational timelines, and quality and performance metrics.
• S upport vendor governance meetings, oversight activities , issue escalation, and resolution to ensure timely and effective trial execution.

Quality Assurance and Regulatory Compliance

• Ensure adherence to ICH-GCP, FDA, EMA, and global regulatory requirements for assigned trials .
• Work with Quality Assurance and the CST to support and ensure ongoing inspection - r eadiness and implement corrective actions as needed.
• Help ensure data integrity and consistent trial conduct across assigned trials .

Cross-Functional Collaboration

• Align cross-functionally on program objectives and study execution plans , including Clinical Site & Trial Operations, Clinical Field Monitoring & Trial Operations, and Clinical Developm ent Systems .
• Work with cross-functional teams to identify and mitigate study delivery risks.
• Provide study-level operational input into program-level…