Scientist Biopreservation

General Summary And Purpose

The Scientist I, Biopreservation is a core team member of the Research & Development Team. This role supports the development, optimization and evaluation of biopreservation workflows for cell and gene therapy (CGT) and regenerative medicine (RM).

• Design and conduct experiments to evaluate biopreservation strategies including cryopreservation, freezing, thawing and cold‑chain storage workflows for mammalian cells and cellular therapeutics.
• Develop and optimize biopreservation formulations and protocols for immune cells, stem cells, and other therapeutic cell types and tissues.
• Perform characterization assays including viability, apoptosis, proliferation and phenotypic characterization.

• Support development of end‑to‑end cell processing workflows involving cryopreserved starting materials and final drug products.
• Evaluate the impact of process parameters (freezing rates, cryoprotectants, formulation buffers, thaw conditions, etc.) on product quality.
• Assist with scale‑up and technology transfer considerations relevant to CGT manufacturing.

• Perform and interpret assays including:
• Flow cytometry
• Cell viability and apoptosis assays
• Metabolic and functional assays
• Post‑thaw recovery kinetics
• Analyze experimental data and generate reports to guide protocol optimization.

• Collaborate with cross‑functional teams including scientific applications, product development and external clients and collaborators.
• Contribute to technical reports, presentations, publications and white papers.
• Participate in interactions with partners and customers evaluating biopreservation methods, including attending seminars and conferences.

• Stay current with advances in biopreservation technologies and cell therapy process development and manufacturing advances.
• Contribute ideas toward next‑generation preservation strategies and stabilization technologies.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

This position reports to the Senior Director of Cell Processing & Biopreservation.

• Deep understanding of the principles of cryopreservation, freeze‑thaw processes and cold‑chain.
• Hands‑on experience in and demonstrated ability to troubleshoot both adherent and in‑suspension mammalian cell cultures.
• Fluency and experience in designing and troubleshooting cell‑based assays and analytical techniques including fluorescent imaging techniques, flow cytometry andICS, ELISA.
• Strong skills in experiment design and DOE, data analysis and statistics, and scientific writing.
• Training or research experience in biopreservation methods, including cryobiology, vitrification methods, lyophilization and cellular stabilization.
• Experience in handling, culture, expansion and manipulation of primary cells including T‑calls and iPSCs.
• Biotechnology background working with primary cells including culturing, expansion and genetic manipulation of immune cells and stem cells, via viral, mRNA or other manipulation techniques.
• Familiar with and demonstrated ability to apply GLP for lab work documentation.
• Demonstrated ability to publish scientific work and skills for presentations at conferences.
• Familiarity with process development concepts relevant to CGT manufacturing.
• Demonstrated initiative to advance the field by generating innovative ideas and proposing solutions to key challenges in biopreservation and CGT/RM.
• Maintain scientific leadership by actively monitoring and studying emerging research and major developments in the field.
• Scientific curiosity and strong problem‑solving skills.
• Ability to design rigorous experiments and interpret complex data.
• Strong communication and collaboration skills.
• Attention to detail and careful documentation.
• Passion for translating fundamental science into real‑world therapeutic impact.

• BSc or MSc in…