Senior Scientist, Conjugation Process Development

Senior Scientist, Conjugation Process Development

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place.

To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.

Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life‑changing medicines to the world.

Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best‑in‑class medicines to patients around the world.

As a Senior Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be a member of our growing Conjugation Process Development team and will lead antibody‑drug conjugate (ADC) process development projects ranging from early‑phase clinical molecules through late‑stage or commercial products.

You will contribute to the development of ADC products targeting cancer to make a meaningful difference in people’s lives. You will be recognized as a technical expert and a scientific contributor. With your deep knowledge of the discipline, you will be an active team member whose decisions impact the project. You will use your scientific judgment to adapt standard methods and techniques by applying prior work experience.

You will forecast and plan resource requirements for your project team. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide team members.

• Independently design, execute, and interpret studies intended to answer a defined question within the defined timeframe; design subsequent experiments upon interpretation of data.
• Monitor results, identify problems, and develop solutions.
• Facilitate technology/assay transfers internally and externally.
• Regularly contribute at the department and project team level and represent the group on multidisciplinary teams.
• May present at national/international forums.
• Author and review technical reports, manufacturing documents, regulatory submissions, and publications.
• Identify areas for process improvement and technology development and propose solutions.

• Bachelor’s Degree with 9 to 11 years of experience, Master’s Degree with 7 to 8 years of experience, or PhD with 0-3 years of experience.
• Degree in chemistry, biochemistry, chemical engineering, or a related field.
• Direct experience with antibodies, proteins, and/or bioconjugation.
• Good understanding of analytical protein characterization (HPLC, IEF, CE‑SDS).
• Willingness to work with highly potent cytotoxic molecules.
• Ability to perform complex data analysis.
• Excellent oral and written communication skills.
• Foundational understanding of organic chemistry, reaction mechanisms, and process development.

• Experience with tangential flow filtration.
• Experience using statistical and data analysis software such as JMP for experimental design, data visualization, and interpretation.
• Experience with GMP manufacturing.
• Familiarity with CMC team function.
• Experience with technology transfer to manufacturing.
• Familiarity with chemical synthesis, protein modification, bioconjugation chemistry, and the application of analytical technologies to process development.

Work Location Assignment:
On Premise

The annual base salary for this position ranges from $93,600.00 to $. In…